2-(2-羟基乙氧基)吡啶-3-醇合成路线 （共 5 条）
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Joseph, Benoit; Benarab, Abdelhakim; Guillaumet, Gerald
Heterocycles, 1994 , vol. 38, # 6 p. 1355 - 1360
反应条件
1: 76 percent / DIAD, PPh3 / tetrahydrofuran / 2 h / Ambient temperature 2: 1.) BuLi, 2.) Cl3CCCl3 / 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, -78 deg C, 10 min View Scheme
参考文献
Joseph, Benoit; Benarab, Abdelhakim; Guillaumet, Gerald
Heterocycles, 1994 , vol. 38, # 6 p. 1355 - 1360
反应条件
hydrogen; palladium on activated charcoal in methanol
P=2327.2 Torr; 16 h;
参考文献
Joseph, Benoit; Benarab, Abdelhakim; Guillaumet, Gerald
Heterocycles, 1994 , vol. 38, # 6 p. 1355 - 1360
反应条件
1: 98 percent / K2CO3 / acetone / 16 h
2: 1.) NaH / 1.) DMF, 30 min, 2.) DMF, 100 deg C, 3 d
3: 98 percent / H2 / 10percent Pd/C / methanol / 16 h / 2327.2 Torr
View Scheme
参考文献
Joseph, Benoit; Benarab, Abdelhakim; Guillaumet, Gerald
Heterocycles, 1994 , vol. 38, # 6 p. 1355 - 1360
反应条件
1: 1.) NaH / 1.) DMF, 30 min, 2.) DMF, 100 deg C, 3 d
2: 98 percent / H2 / 10percent Pd/C / methanol / 16 h / 2327.2 Torr
View Scheme
参考文献
Joseph, Benoit; Benarab, Abdelhakim; Guillaumet, Gerald
Heterocycles, 1994 , vol. 38, # 6 p. 1355 - 1360
