(3R,3AS,6AR)-六氢呋喃并[2,3-B]呋喃-3-醇合成路线 （共 53 条）
反应条件
1: ozone / 0.25 h / -78 - 25 °C / |Inert atmosphere 2: methanol; acetic acid / 3 h / |Inert atmosphere; |Reflux 3: potassium carbonate / methanol / 1 h / 20 °C / |Inert atmosphere 4: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / -10 - 20 °C / |Inert atmosphere 5: sodium methylate / methanol / |Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 31 p. 6228 - 6235
反应条件
1.1: diisobutylaluminium hydride / toluene / 1.45 h / -74 °C / |Inert atmosphere 2.1: hydrogenchloride / tetrahydrofuran; water / 23 h / 20 °C 2.2: 0.33 h View Scheme
反应条件
triethylamine in acetonitrile T=23°C; 7 h;
参考文献
Ghosh, Arun K.; Leshchenko, Sofiya; Noetzel, Marcus
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 7822 - 7829
