phosphate buffer; Krebsiella oxytoca esterase in water T=39°C; pH=7.0;

1: 91 percent / AD-mix β / 2-methyl-propan-2-ol; H2O / 2 h / 20 °C 2: 92 percent / DMAP; Et3N / CH2Cl2 / 2 h / 20 °C 3: 84 percent / t-BuOK / acetonitrile / 12 h / 20 °C 4: 94 percent / TBAF / acetonitrile / 4 h / 20 °C 5: 58 percent / TEMPO; NaClO; NaClO2 / acetonitrile; aq. phosphate buffer / 4 h / 55 °C View Scheme

1.1: 1.69 g / SnBr2 / CH2Cl2 / 20 °C 2.1: 88 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; ethanol; hexane / 24 h / 30 °C / pH 6.0 3.1: 35 percent / nitrosylsulfuric acid / dimethylformamide / 24 h / 20 °C 4.1: SnBr2 / CH2Cl2 / 20 °C 4.2: 92 percent / CH2Cl2 / 20 °C 5.1: 45 percent / immobilized Burkholderia cepacia lipase; phosphate buffer; NaOH / decane; H2O / 38 h / 30 °C / pH 7.0 6.1: 75 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; dimethylformamide; hexane / 24 h / 30 °C / pH 6.0 7.1: nitrosylsulfuric acid / dimethylformamide / 0.5 h / 0 °C 8.1: 13.0 mg / CH2Cl2 9.1: 48 percent / silica gel / diethyl ether 10.1: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme

1.1: Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; ethanol / 18 h / 30 °C / pH 6.0 2.1: SnBr2 / CH2Cl2 / 20 °C 2.2: 92 percent / CH2Cl2 / 20 °C 3.1: 45 percent / immobilized Burkholderia cepacia lipase; phosphate buffer; NaOH / decane; H2O / 38 h / 30 °C / pH 7.0 4.1: 75 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; dimethylformamide; hexane / 24 h / 30 °C / pH 6.0 5.1: nitrosylsulfuric acid / dimethylformamide / 0.5 h / 0 °C 6.1: 13.0 mg / CH2Cl2 7.1: 48 percent / silica gel / diethyl ether 8.1: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme

1: 75 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; dimethylformamide; hexane / 24 h / 30 °C / pH 6.0 2: nitrosylsulfuric acid / dimethylformamide / 0.5 h / 0 °C 3: 13.0 mg / CH2Cl2 4: 48 percent / silica gel / diethyl ether 5: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme

1.1: SnBr2 / CH2Cl2 / 20 °C 1.2: 92 percent / CH2Cl2 / 20 °C 2.1: 45 percent / immobilized Burkholderia cepacia lipase; phosphate buffer; NaOH / decane; H2O / 38 h / 30 °C / pH 7.0 3.1: 75 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; dimethylformamide; hexane / 24 h / 30 °C / pH 6.0 4.1: nitrosylsulfuric acid / dimethylformamide / 0.5 h / 0 °C 5.1: 13.0 mg / CH2Cl2 6.1: 48 percent / silica gel / diethyl ether 7.1: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme

1: 13.0 mg / CH2Cl2 2: 48 percent / silica gel / diethyl ether 3: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme

1: 48 percent / silica gel / diethyl ether 2: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme

1.1: 88 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; ethanol; hexane / 24 h / 30 °C / pH 6.0 2.1: 35 percent / nitrosylsulfuric acid / dimethylformamide / 24 h / 20 °C 3.1: SnBr2 / CH2Cl2 / 20 °C 3.2: 92 percent / CH2Cl2 / 20 °C 4.1: 45 percent / immobilized Burkholderia cepacia lipase; phosphate buffer; NaOH / decane; H2O / 38 h / 30 °C / pH 7.0 5.1: 75 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; dimethylformamide; hexane / 24 h / 30 °C / pH 6.0 6.1: nitrosylsulfuric acid / dimethylformamide / 0.5 h / 0 °C 7.1: 13.0 mg / CH2Cl2 8.1: 48 percent / silica gel / diethyl ether 9.1: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme

1: 45 percent / immobilized Burkholderia cepacia lipase; phosphate buffer; NaOH / decane; H2O / 38 h / 30 °C / pH 7.0 2: 75 percent / Rhodococcus rhodochrous IFO 15564; phosphate buffer / H2O; dimethylformamide; hexane / 24 h / 30 °C / pH 6.0 3: nitrosylsulfuric acid / dimethylformamide / 0.5 h / 0 °C 4: 13.0 mg / CH2Cl2 5: 48 percent / silica gel / diethyl ether 6: 100 percent / Krebsiella oxytoca esterase; phosphate buffer / H2O / 39 °C / pH 7.0 View Scheme