2-苯基-1,3-丙二醇合成路线 （共 45 条）
反应条件
1: 90 percent / pyridine / 24 h / 20 °C
2: sodium azide / dimethylformamide / 24 h / 55 °C
3: 210 mg / H2 / Pd/C / methanol / 24 h / 20 °C
View Scheme
参考文献
Bustos, Eduardo; Gotor-Fernandez, Vicente; Montejo-Bernardo, Jose; Garcia-Granda, Santiago; Gotor, Vicente
Organic Letters, 2007 , vol. 9, # 21 p. 4203 - 4206
反应条件
1: 52 percent / 4-(N,N-dimethylamino)pyridine, Et3N / CH2Cl2 / 12 h / Ambient temperature
2: PDC, 4 Angstroem molecular sieves / CH2Cl2 / 1.5 h / Ambient temperature
3: 1.) n-BuLi / 1) hexane, THF, 0 deg C, 30 min; 2) THF, hexane, 0 deg C, 3 h
4: Bu4NF / tetrahydrofuran / 24 h / Ambient temperature
View Scheme
参考文献
Ihara, Masataka; Katsumata, Akira; Setsu, Fumihito; Tokunaga, Yuji; Fukumoto, Keiichiro
Journal of Organic Chemistry, 1996 , vol. 61, # 2 p. 677 - 684
反应条件
pyridine; thionyl chloride in benzene
3 h;
参考文献
Virtanen, Terttu; Nikander, Hannu
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 2 p. 113 - 116
反应条件
tetrachloromethane; triphenylphosphine in dichloromethane
参考文献
Kawasaki, Masashi; Goto, Michimasa; Kawabata, Shigeki; Kometani, Tadashi
Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 585 - 596
反应条件
1: 2 percent / acetate buffer pH 5 / H2O / 168 h / 30 °C / Gluconobacter roseus IAM 1841
2: diethyl ether
View Scheme
参考文献
Ohta, Hiromichi; Tetsukawa, Hatsuki; Noto, Naoko
Journal of Organic Chemistry, 1982 , vol. 47, # 12 p. 2400 - 2404
