N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯合成路线 （共 5 条）
反应条件
4-methyl-morpholine in chloroform; N,N-dimethyl-formamide T=-5 - 20°C; 1.5 h; Yield given;
参考文献
European Journal of Medicinal Chemistry, , vol. 31, # 2 p. 151 - 157
反应条件
1: N-methylmorpholine / CHCl3 / 0.03 h / -10 °C 2: N-methylmorpholine / CHCl3; dimethylformamide / 1.5 h / -5 - 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 31, # 2 p. 151 - 157
反应条件
1: 86 percent / aq. NaOH / 0.25 h / 0 - 4 °C 2: N-methylmorpholine / CHCl3 / 0.03 h / -10 °C 3: N-methylmorpholine / CHCl3; dimethylformamide / 1.5 h / -5 - 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 31, # 2 p. 151 - 157
反应条件
1: 86 percent / aq. NaOH / 0.25 h / 0 - 4 °C 2: N-methylmorpholine / CHCl3 / 0.03 h / -10 °C 3: N-methylmorpholine / CHCl3; dimethylformamide / 1.5 h / -5 - 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 31, # 2 p. 151 - 157
反应条件
sodium hydroxide 3 h;
参考文献
Gudasheva; Voronina; Ostrovskaya; Rozantsev; Vasilevich; Trofimov; Kravchenko; Skoldinov; Seredenin
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 2 p. 151 - 157
