(E)-beta-氯丙烯酰苯合成路线 （共 28 条）
反应条件
1: benzoyl chloride With AlCl3, aluminium chloride; [C4mpy][Cl] T=25°C; 0.25 h; Inert atmosphere; 2: acetylene T=60°C; 2 h; Product distribution / selectivity;
参考文献
Lonza Ltd
Patent: EP2383248 A1, 2011 ;
Location in patent: Page/Page column 6-7 ;
反应条件
aluminium trichloride in chloroform 1.) 55-65 deg C, 24 h, 2.) 30 min;
参考文献
Padmavathi, Venkatapuram; Reddy, Boggu Jagan Mohan; Padmaja, Adivireddy
Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 2 p. 333 - 335
反应条件
[Co(triphenylphosphane)2Cl2] in benzene T=30°C; 14 h;
参考文献
Iqbal; Srivastava
Tetrahedron, 1991 , vol. 47, # 18-19 p. 3155 - 3170
反应条件
1: 97 percent / aq. NaHCO3 / CH2Cl2 / 4 h 2: 1.) PhSeCl3, 2.) aq.NaHCO3 / 1.) ether, 0 deg C, 2.5 h, 2.) Ch2Cl2, 4 h View Scheme
参考文献
Engman Lars
Journal of Organic Chemistry, 1988 , vol. 53, # 17 p. 4031 - 4037
反应条件
1: 62 percent / diethyl ether / 2 h / Ambient temperature 2: 97 percent / aq. NaHCO3 / CH2Cl2 / 4 h 3: 1.) PhSeCl3, 2.) aq.NaHCO3 / 1.) ether, 0 deg C, 2.5 h, 2.) Ch2Cl2, 4 h View Scheme
参考文献
Engman Lars
Journal of Organic Chemistry, 1988 , vol. 53, # 17 p. 4031 - 4037
反应条件
1: benzoyl chloride With AlCl3, aluminium chloride; [C4mpy][Cl] T=20°C; 0.25 h; 2: acetylene T=60°C; Friedel Crafts type addition; 2 h; optical yield given as percent de;
参考文献
Snelders, Dennis J. M.; Dyson, Paul J.
Organic Letters, 2011 , vol. 13, # 15 p. 4048 - 4051
反应条件
sulfuryl dichloride in chloroform
参考文献
Eberbach, Wolfgang; Roser, Joachim
Heterocycles, 1985 , vol. 23, # 11 p. 2797 - 2802
反应条件
1: 1.) NaH / ether 2: SO2Cl / CHCl3 View Scheme
参考文献
Aitken, R. Alan; Hodgson, Philip K.G.; Morrison, John J.; Oyewale, Adebayo O.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 3 p. 402 - 415
反应条件
T=4°C; 72 h; optical yield given as percent de;
参考文献
Snelders, Dennis J. M.; Dyson, Paul J.
Organic Letters, 2011 , vol. 13, # 15 p. 4048 - 4051
反应条件
phosphorus pentachloride in diethyl ether; dichloromethane Ambient temperature;
参考文献
Naser-Ud-Din; Skattebol, Lars
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1983 , vol. 37, # 3 p. 247 - 248
