2' -脱氧3' -磷酸游离酸合成路线 （共 11 条）
反应条件
1: C49H62N23O28P5 With N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide T=17°C; pH=6; 48 h; 2: C10H15N5O9P2*C6H15N With 1,4-dithio-DL-threitol; adenosine 5'-triphosphoric acid; manganese (II) chloride; N,N'-bis(3-aminopropyl)-1,4-butanediamine T=48°C; pH=8; 17 h; 3: With alkaline phosphatase T=37°C; pH=8; 1 h; Further stages.;
参考文献
Schmitz; Reetz
Organic letters, 1999 , vol. 1, # 11 p. 1729 - 1731
反应条件
1: 98 percent / t-butylmagnesium chloride / tetrahydrofuran / 1 h / Ambient temperature 2: CHCl2COOH / CH2Cl2 / 0.17 h / 25 °C 3: Pd(P(C6H5)3)4, P(C6H5)3, HCOOH, n-C4H9NH2 / tetrahydrofuran / 3.7 h / 50 °C View Scheme
参考文献
Hayakawa, Y.; Wakabayashi, S.; Nobori, T.; Noyori, R.
Tetrahedron Letters, 1987 , vol. 28, # 20 p. 2259 - 2262
反应条件
1: 2,6-dimethyl-pyridine; DMF 2: ueber mehrere Stufen View Scheme
参考文献
Hayes et al.
Journal of the Chemical Society, 1955 , p. 808,810
反应条件
1: NH3; methanol; ethanol 2: 2,6-dimethyl-pyridine; DMF 3: ueber mehrere Stufen View Scheme
参考文献
Hayes et al.
Journal of the Chemical Society, 1955 , p. 808,810
反应条件
pyridine; ammonium hydroxide; acetic acid 1.) 50 deg C, 12 h, 2.) 30 min; Multistep reaction;
参考文献
Jankowska, Jadwiga; Stawinski, Jacek
Bulletin of the Polish Academy of Sciences, Chemistry, 1983 , vol. 31, # 1-2 p. 17 - 22
反应条件
bovine intestinal mucosa phosphodiesterase I; Tris-Cl buffer T=37°C; pH=7.6; 1 h; Enzyme kinetics;
参考文献
Nair, Vasu; Pal, Suresh
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 1 p. 289 - 291
反应条件
cerium(III) chloride; HEPES buffer; oxygen in water T=50°C; other reagents, effect of buffer concentration; Rate constant;
参考文献
Journal of the Chemical Society. Perkin Transactions 2, , # 9 p. 1685 - 1688
反应条件
mit Hilfe eines Enzym-Praeparats aus Darmschleimhaut;
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 224, p. 252,255,256
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 231, p. 96,99
反应条件
dihydrogen peroxide; iron(III) cation; Reduced nicotinamide-adenine dinucleotide in ethanol Fenton Reaction; Reagent/catalyst;
参考文献
Journal of Biomolecular Structure and Dynamics, , vol. 30, # 4 p. 394 - 406
反应条件
dihydrogen peroxide; iron(III) cation; Reduced nicotinamide-adenine dinucleotide in ethanol Fenton Reaction; Reagent/catalyst;
参考文献
Chattopadhyaya, Rajagopal; Goswami, Bhaswati
Journal of Biomolecular Structure and Dynamics, 2012 , vol. 30, # 4 p. 394 - 406
