苄基-[2-(1H-吲哚-3-基)-乙基]-胺合成路线 （共 16 条）
反应条件
hydrogen; palladium on activated charcoal in 2,2,2-trifluoroethanol
3 h;
参考文献
Bailey, Patrick D.; Beard, Mark A.; Dang, Hoa P.T.; Phillips, Theresa R.; Price, Richard A.; Whittaker, James H.
Tetrahedron Letters, 2008 , vol. 49, # 13 p. 2150 - 2153
反应条件
1: 95 percent / NaOH / acetone / -30 °C
2: 98 percent / LiAlH4 / tetrahydrofuran / Heating
View Scheme
参考文献
Czerwinski, Kevin M.; Zificsak, Craig A.; Stevens, John; Oberbeck, Melissa; Randlett, Christopher; King, Melissa; Mennen, Steve
Synthetic Communications, 2003 , vol. 33, # 7 p. 1225 - 1231
反应条件
lithium aluminium tetrahydride
参考文献
Upjohn Co.
Patent: US2870162 , 1954 ;
反应条件
1: diethyl ether
2: LiAlH4
View Scheme
参考文献
Upjohn Co.
Patent: US2870162 , 1954 ;
反应条件
1: diethyl ether
2: LiAlH4
View Scheme
参考文献
Upjohn Co.
Patent: US2870162 , 1954 ;
反应条件
1: 94 percent / TFA / CHCl3 / 0.5 h / 20 °C
2: 100 percent / H2 / Pd/C / 10 h / 20 °C / 3102.89 Torr
3: 70 percent / K2CO3 / CH2Cl2 / 24 h / 20 °C
4: DIBAL-H / CH2Cl2 / 2 h / -79 °C
5: tetrahydrofuran / 12 h / 20 °C
6: 90 percent / Grubbs' 2nd. generation catalyst / toluene / 3 h / 80 °C
View Scheme
参考文献
Chavan, Subhash P.; Sharma, Pallavi; Sivappa; Kalkote, Uttam R.
Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9301 - 9303
