3-(2-氯苯基)-丙醛合成路线 （共 10 条）
反应条件
tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate in N,N-dimethyl-formamide T=45°C; 22 h;
参考文献
Kuwabe; Torraca; Buchwald
Journal of the American Chemical Society, 2001 , vol. 123, # 49 p. 12202 - 12206
Title/Abstract Full Text View citing articles Show Details
Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L.
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
反应条件
pyridinium chlorochromate in dichloromethane T=20°C;
参考文献
WO2012/100734 A1, ;
Page/Page column 33 ;
WO 2012/100734 A1
反应条件
hydrogen; [Rh(cod)Cl]2 entrapped in IL-modified silica sol-gel in n-heptane T=50°C; P=10351 Torr; 12 h; Title compound not separated from byproducts.;
参考文献
European Journal of Organic Chemistry, , # 28 p. 4706 - 4710
反应条件
1: 3-chloro-propionaldehyde diethyl acetal With lithium; 4,4'-di-tert-butylbiphenyl in tetrahydrofuran T=-78°C; 1 h; 2: With zinc dibromide in tetrahydrofuran T=-78 - 20°C; 3: 1-bromo-2-chloro-benzene With Pd(OAc)2(PPh3)2 in tetrahydrofuran T=70°C; Negishi cross-coupling reaction; 24 h; Further stages.;
参考文献
Yus, Miguel; Gomis, Joaquin
European Journal of Organic Chemistry, 2002 , # 12 p. 1989 - 1995
反应条件
C42H36ClIrO2P2*C2H3N; hydrogen in 1,2-dichloro-ethane T=90°C; P=18001.8 Torr; 24 h; AutoclaveInert atmosphereSchlenk technique;
参考文献
Chemistry - A European Journal, , vol. 19, # 50 p. 16906 - 16909
反应条件
1.1: borane-THF / tetrahydrofuran / 0 - 20 °C 1.2: 0 °C 2.1: pyridinium chlorochromate / dichloromethane / 20 °C View Scheme
参考文献
WO2012/100734 A1, ;
WO 2012/100734 A1
反应条件
ammonium cerium (IV) nitrate; MacMillan imidazolidinone in ethylene glycol dimethyl ether T=25°C; 1 h;
参考文献
Zhu, Jin; Yu, Shunting; Lu, Wenchao; Deng, Jing; Li, Jian; Wang, Wei
Tetrahedron Letters, 2012 , vol. 53, # 10 p. 1207 - 1209
反应条件
1: 91 percent / diethyl ether / 0 - 20 °C
2: 79 percent / Pd(OAc)2; Cs2CO3; 2-di-tert-butylphosphanylbiphenyl / toluene / 24 h / 80 °C
View Scheme
参考文献
Kuwabe; Torraca; Buchwald
Journal of the American Chemical Society, 2001 , vol. 123, # 49 p. 12202 - 12206
反应条件
1: 98 percent / sodium borohydride / methanol / 20 °C
2: 87 percent / Pd(OAc)2; Cs2CO3; 2-(di-tert-butylphosphanyl)-1,1'-binaphthyl / toluene / 21 h / 65 °C
View Scheme
参考文献
Kuwabe; Torraca; Buchwald
Journal of the American Chemical Society, 2001 , vol. 123, # 49 p. 12202 - 12206
反应条件
sodium tetrahydroborate in methanol
T=20°C;
参考文献
Kuwabe; Torraca; Buchwald
Journal of the American Chemical Society, 2001 , vol. 123, # 49 p. 12202 - 12206
Title/Abstract Full Text View citing articles Show Details
Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L.
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
