N-苄基-对甲苯磺酸胺合成路线 （共 161 条）
参考文献
Alonso, Emma; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 42 p. 14355 - 14368
参考文献
Holmes; Ingold
Journal of the Chemical Society, 1925 , vol. 127, p. 1810
Full Text Show Details
Carothers; Bickford; Hurwitz
Journal of the American Chemical Society, 1927 , vol. 49, p. 2908
反应条件
1: 1.) Li, naphthalene, 2.) H2O / 1.) THF, -78 deg C, 2 h
2: 91 percent / triethylamine; CH2Cl2 / 2 h / 20 °C
3: 1.) n-BuLi / 1.) THF, hexane, -78 deg C -> 0 deg C, 30 min, 2.) THF, hexane, -78 deg C -> rt, overnight
4: 1.) Li, naphthalene, 2.) H2O / 1.) THF, -78 deg C, 1.5 h
View Scheme
参考文献
Alonso, Emma; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 42 p. 14355 - 14368
反应条件
2: 19 percent / KH / hexamethylphosphoric acid triamide / 72 h / Ambient temperature
View Scheme
参考文献
Townsend, Craig A.; Theis, Alan B.
Journal of Organic Chemistry, 1980 , vol. 45, # 9 p. 1697 - 1699
反应条件
1: 1.) Li, naphthalene, 2.) H2O / 1.) THF, -78 deg C, 2 h
2: 91 percent / triethylamine; CH2Cl2 / 2 h / 20 °C
3: 1.) n-BuLi / 1.) THF, hexane, -78 deg C -> 0 deg C, 30 min, 2.) THF, hexane, -78 deg C -> rt, overnight
4: 1.) Li, naphthalene, 2.) H2O / 1.) THF, -78 deg C - 20 deg C, 2 h
View Scheme
参考文献
Alonso, Emma; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 42 p. 14355 - 14368
反应条件
2: 23 percent / KH / hexamethylphosphoric acid triamide / 72 h / Ambient temperature
3: 56 percent / KH / hexamethylphosphoric acid triamide / 72 h / Ambient temperature
View Scheme
参考文献
Townsend, Craig A.; Theis, Alan B.
Journal of Organic Chemistry, 1980 , vol. 45, # 9 p. 1697 - 1699
参考文献
Li, Man-Bo; Tang, Xiang-Ling; Tian, Shi-Kai
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1980 - 1984
反应条件
sodium hydroxide
durch Propylierung;
参考文献
Carothers; Bickford; Hurwitz
Journal of the American Chemical Society, 1927 , vol. 49, p. 2908
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -78 deg C -> 0 deg C, 30 min, 2.) THF, hexane, -78 deg C -> rt, overnight
2: 1.) Li, naphthalene, 2.) H2O / 1.) THF, -78 deg C, 2 h
View Scheme
参考文献
Alonso, Emma; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 42 p. 14355 - 14368
反应条件
1: 1.) Li, naphthalene, 2.) H2O / 1.) THF, -78 deg C, 2 h
2: 91 percent / triethylamine; CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Alonso, Emma; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 42 p. 14355 - 14368
