N-叔丁氧羰基-L-丙氨酸合成路线 (共 171 条)
反应条件
triethylamine in ethyl acetate; toluene 2 h; Ambient temperature; Yield given. Title compound not separated from byproducts;
参考文献
Gruszecki, Wojciech; Gruszecka, Maria; Bradaczek, Hans
Liebigs Annalen der Chemie, 1988 , p. 331 - 336
反应条件
N,N-dimethyl-formamide in dichloromethane T=0°C; 1 h;
参考文献
Journal of the American Chemical Society, , vol. 120, # 41 p. 10646 - 10652
反应条件
phosphorus trichoride in dichloromethane T=0°C; 2 h;
参考文献
Tetrahedron, , vol. 50, # 30 p. 9051 - 9060
反应条件
4-methyl-morpholine; 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride
参考文献
TOKUYAMA CORPORATION
Patent: EP1178043 A1, 2002 ;
Location in patent: Page 31, 32 ;
反应条件
sodium carbonate in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
Xu, Zhigang; DiCesare, John C.; Baures, Paul W.
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 248 - 254
反应条件
in methanol; diethyl ether; benzene 0.5 h;
参考文献
Singh, Erinprit K.; Ramsey, Deborah M.; McAlpine, Shelli R.
Organic Letters, 2012 , vol. 14, # 5 p. 1198 - 1201
反应条件
in dichloromethane T=20°C; 3 h;
参考文献
Erb, Bernhard; Kucma, Jean-Philippe; Mourey, Sandrine; Struber, Fritz
Chemistry - A European Journal, 2003 , vol. 9, # 11 p. 2582 - 2588
参考文献
Keglevic,D. et al.
Carbohydrate Research, 1972 , vol. 22, p. 245 - 256
反应条件
potassium hydrogensulfate; lithium aluminium tetrahydride in tetrahydrofuran; N,N-dimethyl-formamide
参考文献
Aventis Pharmaceuticals Products Inc.
Patent: US6133409 A1, 2000 ;
反应条件
1: EDC; HOBT; Et3N / dimethylformamide 2: LiAlH4 View Scheme
参考文献
Moore; Leatherwood; Diehl; Selkoe; Wolfe
Journal of Medicinal Chemistry, 2000 , vol. 43, # 18 p. 3434 - 3442