N-叔丁氧羰基-L-丙氨酸合成路线 （共 171 条）
反应条件
(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine in dichloromethane
参考文献
Valverde, Ibai E.; Huxol, Elena; Mindt, Thomas L.
Journal of Labelled Compounds and Radiopharmaceuticals, 2014 , vol. 57, # 4 p. 275 - 278
反应条件
dicyclohexyl-carbodiimide in chloroform
参考文献
Zhou, Zheng Hong; Tang, Yi Long; Li, Kang Ying; Liu, Bing; Tang, Chu Chi
Heteroatom Chemistry, 2003 , vol. 14, # 7 p. 603 - 606
反应条件
1: CH2Cl2 / 0.5 h / 0 °C 2: Et3N / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
White, Jonathan M.; Tunoori, Ashok Rao; Turunen, Brandon J.; Georg, Gunda I.
Journal of Organic Chemistry, 2004 , vol. 69, # 7 p. 2573 - 2576
反应条件
1: With dicyclohexyl-carbodiimide in dichloromethane T=20°C; Dehydration; 1 h; 2: With ammonia in dichloromethane T=0°C; Substitution; 1 h;
参考文献
Kigoshi, Hideo; Yamada, Shiho
Tetrahedron, 1999 , vol. 55, # 42 p. 12301 - 12308
反应条件
borane-THF in tetrahydrofuran T=0°C; other substrates, also with LiAlH4 and DIBAL;
参考文献
Stanfield, C. Freeman; Parker, James E.; Kanellis, Panayiotis
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4799 - 4800
反应条件
1: With dicyclohexyl-carbodiimide in dichloromethane T=20°C; Dehydration; 1 h; 2: With ammonia in dichloromethane T=0°C; Substitution; 1 h;
参考文献
Kigoshi, Hideo; Yamada, Shiho
Tetrahedron, 1999 , vol. 55, # 42 p. 12301 - 12308
反应条件
BBDI in 1,4-dioxane T=20°C; 24 h;
参考文献
Saito, Yukako; Watanabe, Tomokazu; Takahata, Hiroki
Tetrahedron Letters, 2006 , vol. 47, # 18 p. 3099 - 3102
反应条件
triethylamine in tetrahydrofuran
参考文献
Adrio, Javier; Cuevas, Carmen; Manzanares, Ignacio; Joullie, Madeleine M.
Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5129 - 5138
反应条件
4-(N,N-dimethlyamino)pyridine; benzyl alcohol; silica gel in 4-(dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran
参考文献
VON NUSSBAUM, Franz; Beck, Hartmut; Brunner, Nina; Endermann, Rainer; Koebberling, Johannes; Ragot, Jacques; Telser, Joachim; Schuhmacher, Joachim; Anlauf, Sonja; Cancho-Grande, Yolanda; Greschat, Susanne; Militzer, Hans-Christian; Schiffer, Guido
Patent: US2009/203582 A1, 2009 ;
反应条件
triethylamine in various solvent(s) T=83°C; 24 h;
参考文献
Tummatorn, Jumreang; Albiniak, Philip A.; Dudley, Gregory B.
Journal of Organic Chemistry, 2007 , vol. 72, # 23 p. 8962 - 8964
