N-叔丁氧羰基-L-丙氨酸合成路线 （共 171 条）
反应条件
1: 86 percent / NaH / tetrahydrofuran 2: 1.) n-BuLi, (-)-sparteine / 1.) toluene, -78 deg C, 4 h, 2.) toluene, -78 deg C -> room temperature 3: ammonium cerium(IV) nitrate / acetonitrile; H2O / 0.5 h / 0 °C 4: NaIO4, RuCl3*H2O / CCl4; acetonitrile; H2O / 48 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 5 p. 1705 - 1708
反应条件
1: 1.) n-BuLi, (-)-sparteine / 1.) toluene, -78 deg C, 4 h, 2.) toluene, -78 deg C -> room temperature 2: ammonium cerium(IV) nitrate / acetonitrile; H2O / 0.5 h / 0 °C 3: NaIO4, RuCl3*H2O / CCl4; acetonitrile; H2O / 48 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 5 p. 1705 - 1708
反应条件
1: ammonium cerium(IV) nitrate / acetonitrile; H2O / 0.5 h / 0 °C 2: NaIO4, RuCl3*H2O / CCl4; acetonitrile; H2O / 48 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 5 p. 1705 - 1708
参考文献
Journal of the American Chemical Society, , vol. 79, p. 6180,6181
反应条件
HEPES buffer; sodium chloride; calcium chloride; K60E,D189S,D194N mutant trypsin in water; N,N-dimethyl-formamide T=25°C; pH=8.0; Enzymatic reaction; Kinetics; Further Variations:Catalysts;
参考文献
The Journal of organic chemistry, , vol. 67, # 25 p. 9103 - 9106
反应条件
HEPES buffer; sodium chloride; calcium chloride; K60E,D189S,D194N mutant trypsin in water; N,N-dimethyl-formamide T=25°C; pH=8.0; Enzymatic reaction; Kinetics; Further Variations:Catalysts;
参考文献
The Journal of organic chemistry, , vol. 67, # 25 p. 9103 - 9106
反应条件
HEPES buffer; sodium chloride; calcium chloride; K60E,D189S,D194N mutant trypsin in water; N,N-dimethyl-formamide T=25°C; pH=8.0; Enzymatic reaction; Kinetics; Further Variations:Catalysts;
参考文献
The Journal of organic chemistry, , vol. 67, # 25 p. 9103 - 9106
反应条件
HEPES buffer; sodium chloride; calcium chloride; K60E,D189S,D194N mutant trypsin in water; N,N-dimethyl-formamide T=25°C; pH=8.0; Enzymatic reaction; Kinetics; Further Variations:Catalysts;
参考文献
The Journal of organic chemistry, , vol. 67, # 25 p. 9103 - 9106
反应条件
HEPES buffer; sodium chloride; calcium chloride; K60E,D189S,D194N mutant trypsin in water; N,N-dimethyl-formamide T=25°C; pH=8.0; Enzymatic reaction; Kinetics; Further Variations:Catalysts;
参考文献
The Journal of organic chemistry, , vol. 67, # 25 p. 9103 - 9106
反应条件
HEPES buffer; sodium chloride; calcium chloride; K60E,D189S,D194N mutant trypsin in water; N,N-dimethyl-formamide T=25°C; pH=8.0; Enzymatic reaction; Kinetics; Further Variations:Catalysts;
参考文献
The Journal of organic chemistry, , vol. 67, # 25 p. 9103 - 9106
