反应条件
1: 76 percent / B2H6*THF / tetrahydrofuran / 1.) 0 deg C, 2 h, 2.) r.t., 1 h 2: 87 percent / SO3*pyridine, Et3N / dimethylsulfoxide / 2.5 h / 7 - 8 °C 3: 1.) i-Pr2N, n-BuLi, MgBr2*Et2O / 1.) THF, hexane, -78 deg C, 30 min; -78 deg C to r.t., 2 h; -78 deg C, 1 h, 2.) THF, -95 deg C, 2 h 4: 62 percent / BF3*Et2O / CH2Cl2 / 1 h / -78 °C 5: 57 percent / potassium tert-butoxide / tetrahydrofuran / 0.08 h / -20 - -15 °C 6: 94 percent / H2 / 10percent Pd/C / methanol / 12 h / Ambient temperature View Scheme
参考文献
Roux, Florence; Maugras, Isabelle; Poncet, Joel; Niel, Gilles; Jouin, Patrick
Tetrahedron, 1994 , vol. 50, # 18 p. 5345 - 5360
