5-苯基-1H-嘧啶-2,4-二酮合成路线 (共 15 条)
反应条件
1: sodium; diethyl ether / Erwaermen des Reaktionsprodukts mit Thioharnstoff in Aethanol 2: aqueous chloroacetic acid View Scheme
参考文献
Journal of the American Pharmaceutical Association (1912-1977), , vol. 44, p. 545,547
参考文献
Synlett, , # 9 p. 1394 - 1398
参考文献
Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 77 - 94
参考文献
Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 77 - 94
反应条件
triethyl amine hydrochloride; trichlorophosphate
T=120°C; 72 h; Heating / reflux;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/37814 A1, 2004 ;
Location in patent: Page 180-181 ;
WO 2004/037814 A1