反应条件
1: 88 percent / K2CO3 / methanol / 60 h / Ambient temperature 2: 90 percent / 2,6-lutidine / CH2Cl2 3: 1.) dicyclohexylmagnesium bromide / 1.) THF, -65 to -50 deg C, 35 min, 2.) THF, -65 to -50 deg C, 40 min 4: 93 percent / TBAF / tetrahydrofuran / 34 h / Ambient temperature 5: 3 Angstroem molecular sieves, TFA / CH2Cl2 / 0.6 h / Ambient temperature View Scheme
参考文献
Kocienski, Philip J.; Brown, Richard C. D.; Pommier, Agnes; Procter, Martin; Schmidt, Bernd
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1998 , # 1 p. 9 - 40
