2-氯-N-(2,4-二甲氧基苯基)烟酰胺合成路线 (共 2 条)
反应条件
pyridine; N,N-dimethyl-formamide in dichloromethane T=0°C; 90 h;
参考文献
Wright, Stephen W.; Petraitis, Joseph J.; Abelman, Matthew M.; Batt, Douglas G.; Bostrom, Lori L.; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 19 p. 3071 - 3078
反应条件
1: oxalyl chloride, DMF / CH2Cl2 / 0.67 h / Heating 2: 85 percent / pyridine, DMF / CH2Cl2 / 90 h / 0 °C View Scheme
参考文献
Wright, Stephen W.; Petraitis, Joseph J.; Abelman, Matthew M.; Batt, Douglas G.; Bostrom, Lori L.; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 19 p. 3071 - 3078