5-氨基-6-溴-2,3-二氢-1H-茚-1-酮合成路线 (共 3 条)
反应条件
hydrogenchloride 1 h; Heating;
参考文献
Li; Black; Chan; Ford-Hutchinson; Gauthier; Gordon; Guay; Kargman; Lau; Mancini; Ouimet; Roy; Vickers; Wong; Young; Zamboni; Prasit
Journal of Medicinal Chemistry, 1995 , vol. 38, # 25 p. 4897 - 4905
反应条件
1: 85 percent / CH2Cl2 / 0.5 h 2: 80 percent / Br2, HOAc / 0.25 h / 10 °C 3: 80 percent / CrO3, HOAc / 0.25 h / 50 - 55 °C 4: 100 percent / 6 M aq. HCl / 1 h / Heating View Scheme
参考文献
Li; Black; Chan; Ford-Hutchinson; Gauthier; Gordon; Guay; Kargman; Lau; Mancini; Ouimet; Roy; Vickers; Wong; Young; Zamboni; Prasit
Journal of Medicinal Chemistry, 1995 , vol. 38, # 25 p. 4897 - 4905
反应条件
1: 80 percent / Br2, HOAc / 0.25 h / 10 °C 2: 80 percent / CrO3, HOAc / 0.25 h / 50 - 55 °C 3: 100 percent / 6 M aq. HCl / 1 h / Heating View Scheme
参考文献
Scheigetz; Zamboni; Roy
Synthetic Communications, 1995 , vol. 25, # 18 p. 2791 - 2806