3-(4-甲氧基苯基)丙酸甲酯合成路线 （共 45 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=25°C; P=2327.2 Torr; 1 h;
参考文献
THE UNIVERSITY OF HONG KONG
Patent: WO2007/41923 A1, 2007 ;
Location in patent: Page/Page column 19 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
The Green Cross Corporation
Patent: US5635527 A1, 1997 ;
反应条件
Novozym 435; acylase I from Aspergillus melleus; amano lipase AK from pseudomonas fluorescens; lipase from wheat germ; papaine in toluene T=40°C; 48 h; Enzymatic reaction; Mechanism;
参考文献
Zysk, Malgorzata; Zadlo, Anna; Brodzka, Anna; Wisniewska, Catalina; Ostaszewski, Ryszard
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 102, p. 225 - 229
反应条件
thionyl chloride; sodium chloride; sodium hydrogencarbonate in methanol; ethyl acetate
参考文献
Chugai Seiyaku Kabushiki Kaisha
Patent: US4965405 A1, 1990 ;
反应条件
1: 3-(4-methoxyphenyl)-propionic acid With 1H-imidazole; iodine; tris-(o-tolyl)phosphine in dichloromethane T=20°C; Garegg-Samuelsson type reaction; 0.0833333 h; 2: methanol in dichloromethane T=20°C; Garegg-Samuelsson type reaction;
参考文献
Morcillo, Sara P.; Alvarez De Cienfuegos, Luis; Mota, Antonio J.; Justicia, Jose; Robles, Rafael
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2277 - 2281
反应条件
1: With sodium acetate in N,N-dimethyl acetamide T=120°C; Heck reaction; Inert atmosphere; 2: With hydrogen in N,N-dimethyl acetamide T=20 - 120°C; P=760.051 Torr;
参考文献
Advanced Synthesis and Catalysis, , vol. 350, # 16 p. 2544 - 2550
反应条件
hydrazine hydrate in ethanol 5.5 h; Reflux;
参考文献
Chen, Hao; Wang, Jianmin; Hong, Xuechuan; Zhou, Hai-Bing; Dong, Chune
Canadian Journal of Chemistry, 2012 , vol. 90, # 9 p. 758 - 761
反应条件
1: p-MeO-cinnamaldehyde With trimethylsilyl cyanide; 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=0°C; 0.166667 h; Inert atmosphere; 2: methanol in tetrahydrofuran T=0°C; 0.333333 h; Inert atmosphere;
参考文献
Kaise, Hiromi; Shimokawa, Jun; Fukuyama, Tohru
Organic Letters, 2014 , vol. 16, # 3 p. 727 - 729
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C; 4 h;
参考文献
Taylor, James E.; Daniels, David S. B.; Smith, Andrew D.
Organic Letters, 2013 , vol. 15, # 23 p. 6058 - 6061
反应条件
bis(cyclopentadienyl)titanium dichloride; manganese; chloro-trimethyl-silane; triphenylphosphine; nickel dichloride in tetrahydrofuran T=50°C; 16 h; Inert atmosphere;
参考文献
Marquez, Irene R.; Miguel, Delia; Millan, Alba; Marcos, M. Luisa; De Cienfuegos, Luis Alvarez; Campana, Araceli G.; Cuerva, Juan M.
Journal of Organic Chemistry, 2014 , vol. 79, # 4 p. 1529 - 1541
