3-(4-甲氧基苯基)丙酸甲酯合成路线 （共 45 条）
反应条件
1: 92 percent / Br2; AlCl3 / CH2Cl2 / 0.33 h / 0 °C 2: 98 percent / NaOH / methanol; H2O / 2.5 h / 20 °C View Scheme
参考文献
Bryant, Vashti C.; Kishore Kumar; Nyong, Abijah M.; Natarajan, Amarnath
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 245 - 248
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1932 , vol. 270, p. 353,359
反应条件
diisobutylaluminium hydride in dichloromethane T=-80°C;
参考文献
Rogano, Frank; Froidevaux, Georges; Rueedi, Peter
Helvetica Chimica Acta, 2010 , vol. 93, # 7 p. 1299 - 1312
反应条件
samarium diiodide; water; triethylamine in tetrahydrofuran T=20°C; 2 h; Inert atmosphere;
参考文献
Szostak, Michal; Spain, Malcolm; Procter, David J.
Chemical Communications, 2011 , vol. 47, # 37 p. 10254 - 10256
参考文献
E. R. Squibb and Sons, Inc.
Patent: US5100889 A1, 1992 ;
反应条件
1: iodine; silver sulphate / methanol / 1 h / 20 °C 2: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / 1,4-dioxane; dimethyl sulfoxide / 17 h / 50 - 80 °C / Inert atmosphere View Scheme
参考文献
Shao, Pengcheng Patrick; Sun, Wanying; Katipally, Revathi Reddy; Vachal, Petr; Ye, Feng; Liu, Jian; Sha, Deyou
Patent: US2013/109649 A1, 2013 ;
反应条件
1: 94 percent / water, KOH / methanol / 2 h / 25 °C 2: 63 percent / polyphosphoric acid / 0.08 h / 120 °C View Scheme
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
1: NaOH / methanol; H2O / 3 h / Heating 2: oxalyl chloride / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Yang, Dan; Wong, Man-Kin; Yan, Zheng
Journal of Organic Chemistry, 2000 , vol. 65, # 13 p. 4179 - 4184
反应条件
potassium hydroxide; water in methanol T=25°C; 2 h;
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
hydrazine hydrate T=110 - 120°C;
参考文献
Prata, Jose V.; Clemente, Dina-Telma S.; Prabhakar, Sundaresan; Lobo, Ana M.; Mourato, Isabel; Branco, Paula S.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 4 p. 513 - 528
