(3S,4S)-4-[(芴甲氧羰基)氨基]-3-羟基-6-甲基庚酸合成路线 （共 5 条）
反应条件
hydrogenchloride in 1,4-dioxane T=70°C; Yield given;
参考文献
Tetrahedron Letters, , vol. 35, # 10 p. 1557 - 1560
反应条件
1: (4S,5S)-ethyl (4-isobutyl-2-oxo-oxazolidin-5-yl)acetate With lithium hydroxide in methanol T=20°C; 1.5 h; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With triethylamine in methanol T=20°C; 0.25 h; Further stages.;
参考文献
Konno, Hiroyuki; Kubo, Kanako; Makabe, Hidefumi; Toshiro, Emi; Hinoda, Naoyuki; Nosaka, Kazuto; Akaji, Kenichi
Tetrahedron, 2007 , vol. 63, # 38 p. 9502 - 9513
反应条件
1.1: 68 percent / triethylamine; mesyl chloride / CH2Cl2 / 3 h / 20 °C 2.1: aq. LiOH / aq. methanol / 1.5 h / 20 °C 2.2: 75 percent / triethylamine / aq. methanol / 0.25 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 38 p. 9502 - 9513
反应条件
1: triethylamine / tetrahydrofuran / Ambient temperature 2: ethyl acetate 3: NaBH4 / CH2Cl2; acetic acid 4: 2N HCl / dioxane / 70 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 10 p. 1557 - 1560
反应条件
1: NaBH4 / CH2Cl2; acetic acid 2: 2N HCl / dioxane / 70 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 10 p. 1557 - 1560
