2,2-二氟-1,3-苯并二恶茂合成路线 （共 22 条）
反应条件
(HF)10-pyridine T=20°C; 2 h;
参考文献
Saint-Jalmes, Laurent
Journal of Fluorine Chemistry, 2006 , vol. 127, # 1 p. 85 - 90
反应条件
potassium fluoride in 1.4-dicyano 1-butene
反应条件
bromine in tetrachloromethane
参考文献
FMC Corporation
Patent: US4895871 A1, 1990 ;
反应条件
bromine; hydrogen fluoride; titanium tetrachloride T=0 - 20°C; 2.33333 h;
参考文献
LANXESS Deutschland GmbH
Patent: EP1595877 A1, 2005 ;
Location in patent: Page/Page column 4 ;
反应条件
1: With hydrogen fluoride; boron trifluoride T=0°C; 1 h; 2: 2,2-difluoro-1,3-benzodioxole T=0 - 55°C; 17.5 h; 3: With potassium hydroxide; sulfuric acid; water more than 3 stages;
参考文献
Pleschke, Axel; Marhold, Albrecht
Patent: US2005/277692 A1, 2005 ;
Location in patent: Page/Page column 3 ;
反应条件
1: 27 percent / sec-butyllithium / tetrahydrofuran; cyclohexane / 3 h / -75 °C 2: 89 percent / potassium hydroxide / diethyl ether; H2O / 15 h / 25 °C 3: 71 percent / 18-crown-6 / acetonitrile / 20 h / Heating View Scheme
参考文献
Schlosser, Manfred; Gorecka, Joanna; Castagnetti, Eva
European Journal of Organic Chemistry, 2003 , # 3 p. 452 - 462
反应条件
LiNHOCH3; sec.-butyllithium in diethyl ether T=-15°C; 2 h;
参考文献
Schlosser, Manfred; Gorecka, Joanna; Castagnetti, Eva
European Journal of Organic Chemistry, 2003 , # 3 p. 452 - 462
反应条件
sec.-butyllithium in tetrahydrofuran; cyclohexane T=-75°C;
参考文献
Schlosser, Manfred; Gorecka, Joanna; Castagnetti, Eva
European Journal of Organic Chemistry, 2003 , # 3 p. 452 - 462
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran; hexane
参考文献
Ciba-Geigy Corporation
Patent: US5194628 A1, 1993 ;
反应条件
sec.-butyllithium in tetrahydrofuran; cyclohexane T=-75°C; 3 h;
参考文献
Schlosser, Manfred; Gorecka, Joanna; Castagnetti, Eva
European Journal of Organic Chemistry, 2003 , # 3 p. 452 - 462
