反应条件
1.1: triethylamine / dichloromethane / -5 - 0 °C
2.1: sulfuric acid / acetic acid / 20 °C
3.1: sodium nitrate
3.2: 0 - 5 °C
4.1: hydrogenchloride; water / methanol / Heating
5.1: triethylamine / 1,4-dioxane / 20 °C
View Scheme
参考文献
Watson, Nigel S.; Adams, Carl; Belton, David; Brown, David; Burns-Kurtis, Cynthia L.; Chaudry, Laiq; Chan, Chuen; Convery, Maire A.; Davies, David E.; Exall, Anne M.; Harling, John D.; Irvine, Stephanie; Irving, Wendy R.; Kleanthous, Savvas; McLay, Iain M.; Pateman, Anthony J.; Patikis, Angela N.; Roethke, Theresa J.; Senger, Stefan; Stelman, Gary J.; Toomey, John R.; West, Robert I.; Whittaker, Caroline; Zhou, Ping; Young, Robert J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1588 - 1592