2-(2-氨基苯基)-2-丙醇合成路线 (共 13 条)
反应条件
in tetrahydrofuran T=20°C; Grignard reaction; 2 h;
参考文献
Bowman, W. Russell; Fletcher, Anthony J.; Pedersen, Jan M.; Lovell, Peter J.; Elsegood, Mark R.J.; Hernandez Lopez, Elena; McKee, Vickie; Potts, Graeme B.S.
Tetrahedron, 2007 , vol. 63, # 1 p. 191 - 203
反应条件
methylmagnesium bromide in tetrahydrofuran; toluene
参考文献
Merck and Co., Inc.
Patent: US5665719 A1, 1997 ;
US 5665719 A
反应条件
methyl-magnesium iodide in diethyl ether
参考文献
Chevron Research Company
Patent: US4030906 A1, 1977 ;
反应条件
in diethyl ether T=20°C; 2 h;
参考文献
Yao, Sheng; Gallenkamp, Daniel; Woelfel, Katharina; Lueke, Bettina; Schindler, Michael; Scherkenbeck, Juergen
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 15 p. 4669 - 4678
反应条件
in diethyl ether T=20°C; 1 h;
参考文献
Oka, Hiroyuki; Tamura, Tomoki; Miura, Yozo; Teki, Yoshio
Journal of Materials Chemistry, 2001 , vol. 11, # 5 p. 1364 - 1369
反应条件
in tetrahydrofuran T=0°C;
参考文献
Kern, Jeffrey C.; Terefenko, Eugene A.; Fensome, Andrew; Unwallla, Ray; Wrobel, Jay; Zhu, Yuan; Cohen, Jeffrey; Winneker, Richard; Zhang, Zhiming; Zhang, Puwen
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 1 p. 189 - 192
反应条件
in diethyl ether Grignard reaction;
参考文献
Pigeon, Pascal; Decroix, Bernard
Synthetic Communications, 1998 , vol. 28, # 13 p. 2507 - 2516
反应条件
magnesium 1) = deg C, diethyl ether, 2) 1 hr. reflux; Yield given. Multistep reaction;
参考文献
Gromachevskaya; Kosulina; Borodavko
Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 8 p. 1068 - 1077
参考文献
U.S. Rubber Co.
Patent: US2086186 , 1933 ;
反应条件
pyridine in tetrahydrofuran
参考文献
Boehringer Ingelheim International GmbH
Patent: US2007/37781 A1, 2007 ;
Location in patent: Page/Page column 36-37 ;