反应条件
1: pyridine, Dess-Martin periodinane / CH2Cl2 / 2 h / 25 °C
2: t-BuOK / tetrahydrofuran / 1.) r.t., 40 min, 2.) -60 to -40 deg C, 1 h; -42 to -20 deg C, 3 h
3: 98 percent / PPTS / methanol / 3.5 h / 25 °C
4: 89 percent / imidazole / CH2Cl2 / 18 h / 25 °C
5: 95 percent / aq. AcOH / tetrahydrofuran / 4 h / 25 °C
6: 87 percent / Dess-Martin periodinane / CH2Cl2 / 0.42 h / 25 °C
7: 91 percent / 2-methyl-2-butene, aq. NaClO2, aq. NaH2PO4 / 2-methyl-propan-2-ol / 0.67 h / 25 °C
8: Et3N / toluene / 2 h / 25 °C
9: DMAP / toluene / 3 h / 60 °C
10: 89 percent / aq. NaIO4 / methanol / 2.5 h / 35 °C
11: 1.) pyridine, TFAA, 2.) NaHCO3 / 1.) CH2Cl2, 25 deg C, 1 h, 2.) MeOH, 3 deg C, 1 h
12: TiCl4 / CH2Cl2 / 3 h / -78 - -15 °C
13: aq. HF / acetonitrile / 2 h / Ambient temperature
14: 72 percent / O2, CuCl, H2O / PdCl2 / dimethylformamide / 15 h / 25 °C
15: 41 percent / TESOTf, 2,6-lutidine / CH2Cl2 / 4 h / 25 °C
View Scheme
参考文献
Oikawa, Masato; Ueno, Tohru; Oikawa, Hideaki; Ichihara, Akitami
Journal of Organic Chemistry, 1995 , vol. 60, # 16 p. 5048 - 5068
