(3aS,8aR)-3-(4,5-脱水-2,3-二脱氧-2-(苯基甲基)-D-赤式-戊酮基)-3,3a,8,8a-四氢-2,2-二甲基-2H-茚并[1,2-d]恶唑合成路线 （共 11 条）
反应条件
sodium bromide constant current electrolysis (undivided electrochemical cell, MeCN/H20);
参考文献
Rossen; Volante; Reider
Tetrahedron Letters, 1997 , vol. 38, # 5 p. 777 - 778
参考文献
Rossen; Volante; Reider
Tetrahedron Letters, 1997 , vol. 38, # 5 p. 777 - 778
反应条件
sodium methylate in methanol T=25°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Maligres; Weissman; Upadhyay; Cianciosi; Reamer; Purick; Sager; Rossen; Eng; Askin; Volante; Reider
Tetrahedron, 1996 , vol. 52, # 9 p. 3327 - 3338
反应条件
lithium hexamethyldisilazane in tetrahydrofuran 1.) -50 to -45 deg C, 2 h; 2.) -45 to -40 deg C, 1 h; 3.) warm to -25 deg C, 1 h; 4.) -25 to -22 deg C, 4 h;
参考文献
Askin, David; Eng, Kan K.; Rossen, Kai; Purick, Robert M.; Wells, Kenneth M.; et al.
Tetrahedron Letters, 1994 , vol. 35, # 5 p. 673 - 676
反应条件
1: 1.) n-BuLi / 2.) -30 deg C 2: t-amylOK View Scheme
参考文献
Askin, David; Eng, Kan K.; Rossen, Kai; Purick, Robert M.; Wells, Kenneth M.; et al.
Tetrahedron Letters, 1994 , vol. 35, # 5 p. 673 - 676
反应条件
potassium 2-methyl-2-butoxide Yield given;
参考文献
Askin, David; Eng, Kan K.; Rossen, Kai; Purick, Robert M.; Wells, Kenneth M.; et al.
Tetrahedron Letters, 1994 , vol. 35, # 5 p. 673 - 676
反应条件
n-butyllithium 2.) -30 deg C; Yield given. Yields of byproduct given;
参考文献
Askin, David; Eng, Kan K.; Rossen, Kai; Purick, Robert M.; Wells, Kenneth M.; et al.
Tetrahedron Letters, 1994 , vol. 35, # 5 p. 673 - 676
反应条件
n-butyllithium Yield given. Yields of byproduct given;
参考文献
Askin, David; Eng, Kan K.; Rossen, Kai; Purick, Robert M.; Wells, Kenneth M.; et al.
Tetrahedron Letters, 1994 , vol. 35, # 5 p. 673 - 676
反应条件
2: HCl / propan-2-ol View Scheme
参考文献
Coburn, Craig A.; Young, Mary Beth; Hungate, Randall W.; Isaacs, Richard C.A.; Vacca, Joseph P.; Huff, Joel R.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 16 p. 1937 - 1940
反应条件
1: IPA / Heating 2: 6N HCl View Scheme
参考文献
Askin, David; Eng, Kan K.; Rossen, Kai; Purick, Robert M.; Wells, Kenneth M.; et al.
Tetrahedron Letters, 1994 , vol. 35, # 5 p. 673 - 676
