2-氨基-6-溴苯并噻唑合成路线 （共 37 条）
参考文献
Hunter et al.
Journal of the Chemical Society, 1959 , p. 784,787
参考文献
Hunter et al.
Journal of the Chemical Society, 1959 , p. 784,787
反应条件
1: 63 percent / ethanol / 15 h / Heating
2: 50percent aq. KOH / Heating
3: 82 percent / sodium carbonate / ethanol / 10 h / Heating
View Scheme
参考文献
Lin; Kasina
Journal of Heterocyclic Chemistry, 1981 , vol. 18, # 4 p. 759 - 761
反应条件
1: 63 percent / ethanol / 15 h / Heating
2: 50percent aq. KOH / Heating
3: 82 percent / sodium carbonate / ethanol / 10 h / Heating
4: 85 percent / copper powder, cuprous iodide, sodium carbonate / dimethylformamide / 12 h / Heating
View Scheme
参考文献
Lin; Kasina
Journal of Heterocyclic Chemistry, 1981 , vol. 18, # 4 p. 759 - 761
反应条件
pyridine
6 h; Reflux;
参考文献
Sharma, Pratibha; Kumar, Ashok; Kumari, Prerna; Singh, Jitendra; Kaushik
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1136 - 1148
反应条件
1.1: pyridine / 4 h / Reflux
2.1: pyridine / 3 h / 0 - 5 °C
3.1: sodium dithionite
4.1: sulfuric acid / ethanol; benzene / Reflux
4.2: Cooling with ice
View Scheme
参考文献
Sharma, Pratibha; Kumar, Ashok; Kumari, Prerna; Singh, Jitendra; Kaushik
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1136 - 1148
反应条件
in ethanol
14 h; Heating;
参考文献
Krasovskii,A.N. et al.
Pharmaceutical Chemistry Journal, 1977 , vol. 11, # 7 p. 900 - 902
Khimiko-Farmatsevticheskii Zhurnal, 1977 , vol. 11, # 7 p. 25 - 27
