3-(2,4-二甲基苯甲酰基)丙酸合成路线 （共 8 条）
参考文献
Ciba-Geigy Corporation
Patent: US5525736 A1, 1996 ;
反应条件
nitromethane; water; silver perchlorate
参考文献
Journal of the Chemical Society, , p. 1718,1725
反应条件
sodium hydroxide; sodium hypochlorite
参考文献
Reinheimer; List
Ohio Journal of Science, 1957 , vol. 57, p. 26
反应条件
1: palladium; acetic acid / 50 °C / 2206.5 Torr / Hydrogenation 2: polyphosphoric acid View Scheme
参考文献
Mosby
Journal of Organic Chemistry, 1953 , vol. 18, p. 485,488
反应条件
palladium; acetic acid T=50°C; P=2206.5 Torr; Hydrogenation;
参考文献
Mosby
Journal of Organic Chemistry, 1953 , vol. 18, p. 485,488
参考文献
Krollpfeiffer; Schaefer
Chemische Berichte, 1923 , vol. 56, p. 630
Full Text Show Details
Barnett; Sanders
Journal of the Chemical Society, 1933 , p. 434,436
反应条件
acetyl chloride
0.25 h; Heating;
参考文献
Tsolomitis, A.; Sandris, C.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1545 - 1548
反应条件
1: (COCl)2 / CH2Cl2; dimethylformamide / Ambient temperature
2: triethylamine / CH2Cl2 / Ambient temperature
3: 97 percent / 37 percent HCl, water, H2 / 10 percent Pd/C / methanol / 2585.7 Torr / Ambient temperature; Parr hydrogenator
4: 91 percent / diethyl ether / 24 h / Ambient temperature
5: 94 percent / PPA / 4 h / Ambient temperature
View Scheme
参考文献
Parlow, John J.
Tetrahedron, 1994 , vol. 50, # 11 p. 3297 - 3314
