(R)-N-叔丁氧羰基-3-氨基-3-苯基丙-1-醇合成路线 （共 10 条）
反应条件
hydrogen in diethyl ether; ethanol T=50°C; P=760.051 Torr; 8 h;
参考文献
Hatano, Manabu; Moriyama, Katsuhiko; Maki, Toshikatsu; Ishihara, Kazuaki
Angewandte Chemie - International Edition, 2010 , vol. 49, # 22 p. 3823 - 3826
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 12 h;
参考文献
Davies, Stephen G.; Garner, A. Christopher; Roberts, Paul M.; Smith, Andrew D.; Sweet, Miles J.; Thomson, James E.
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 14 p. 2753 - 2768
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; Inert atmosphere;
参考文献
Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lentini, Giovanni; Franchini, Carlo; De Bellis, Michela; De Luca, Annamaria; Camerino, Diana Conte
Chirality, 2010 , vol. 22, # 3 p. 299 - 307
反应条件
1: With borane-THF in tetrahydrofuran T=0°C; Inert atmosphere; 2: With water; dihydrogen peroxide; sodium hydroxide in tetrahydrofuran T=20°C; 24 h; Inert atmosphere;
参考文献
Zheng, Bao-Hui; Ding, Chang-Hua; Hou, Xue-Long
Synlett, 2011 , # 15 art. no. W12011ST, p. 2262 - 2264
反应条件
1.1: bis(η3-allyl-μ-chloropalladium(II)); C37H35FeN2O3P; potassium carbonate / dichloromethane / 30 h / 20 °C / Inert atmosphere 2.1: samarium diiodide; 1,2-di-iodoethane / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 3.1: borane-THF / tetrahydrofuran / 0 °C / Inert atmosphere 3.2: 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Synlett, , # 15 art. no. W12011ST, p. 2262 - 2264
反应条件
1.1: bis(η3-allyl-μ-chloropalladium(II)); potassium phosphate; C37H35FeN2O3P / dichloromethane / 22 h / 20 °C / Inert atmosphere 2.1: samarium diiodide; 1,2-di-iodoethane / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 3.1: borane-THF / tetrahydrofuran / 0 °C / Inert atmosphere 3.2: 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Synlett, , # 15 art. no. W12011ST, p. 2262 - 2264
反应条件
1.1: samarium diiodide; 1,2-di-iodoethane / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 2.1: borane-THF / tetrahydrofuran / 0 °C / Inert atmosphere 2.2: 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Synlett, , # 15 art. no. W12011ST, p. 2262 - 2264
反应条件
1.1: bis(η3-allyl-μ-chloropalladium(II)); C37H35FeN2O3P; potassium carbonate / dichloromethane / 48 h / 20 °C / Inert atmosphere 2.1: samarium diiodide; 1,2-di-iodoethane / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 3.1: borane-THF / tetrahydrofuran / 0 °C / Inert atmosphere 3.2: 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Synlett, , # 15 art. no. W12011ST, p. 2262 - 2264
反应条件
1.1: bis(η3-allyl-μ-chloropalladium(II)); C37H35FeN2O3P; potassium carbonate / dichloromethane / 30 h / 20 °C / Inert atmosphere 2.1: samarium diiodide; 1,2-di-iodoethane / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 3.1: borane-THF / tetrahydrofuran / 0 °C / Inert atmosphere 3.2: 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Synlett, , # 15 art. no. W12011ST, p. 2262 - 2264
反应条件
1.1: bis(η3-allyl-μ-chloropalladium(II)); C37H35FeN2O3P; potassium carbonate / dichloromethane / 30 h / 20 °C / Inert atmosphere 2.1: samarium diiodide; 1,2-di-iodoethane / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 3.1: borane-THF / tetrahydrofuran / 0 °C / Inert atmosphere 3.2: 24 h / 20 °C / Inert atmosphere View Scheme
参考文献
Synlett, , # 15 art. no. W12011ST, p. 2262 - 2264
