N-(2’,6’-二甲苯基 )-2-哌啶甲酰胺合成路线 （共 13 条）
反应条件
sodium ethanolate Erwaermen des Reaktionsprodukts mit wss. HCl;
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 11, p. 1183,1184
反应条件
1: With (2R,3S)-(-)-di-O-benzoyl tartaric acid in isopropyl alcohol T=20°C; 1.5 h; Reflux; 2: With water; sodium hydroxide in ethyl acetate
参考文献
PHARMATHEN S.A.
Patent: WO2009/89842 A1, 2009 ;
Location in patent: Page/Page column 6-7 ;
反应条件
Chiralpak IC column from Chiral Technologies (West Chester/PA, U.S.A.) in ethanol; anhydrous butyl ether; diethylamine T=25°C; Resolution of racemate;
参考文献
Von Langermann, Jan; Kaspereit, Malte; Shakeri, Mozaffar; Lorenz, Heike; Hedberg, Martin; Jones, Matthew J.; Larson, Kerstin; Herschend, Bjoern; Arnell, Robert; Temmel, Erik; Baeckvall, Jan-Erling; Kienle, Achim; Seidel-Morgenstern, Andreas
Organic Process Research and Development, 2012 , vol. 16, # 2 p. 343 - 352
