反应条件
1: SOCl2 2: 1.) NaN3, 2.) H2O, 4.) NaOH, 5.) HCl 3: 1.) 98percent sulfuric acid, NaNO2, 2.) CuCl2, 36percent aq. HCl / 1.) acetic acid, 10 deg C, 1 h, 2.) acetic acid, RT, 1 h 4: H2 / 10percent Pd/C / ethyl acetate / 1 h / 760 Torr View Scheme
参考文献
Kimura; Watanabe; Matsui; Hayashi; Tanaka; Ohtsuka; Saeki; Kogushi; Kabayashi; Akasaka; Yamagishi; Saitou; Yamatsu
Journal of Medicinal Chemistry, 1993 , vol. 36, # 11 p. 1641 - 1653
