1: BOC-glycine With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 1.5 h; Inert atmosphere; 2: propargyl bromide in N,N-dimethyl-formamide; toluene; mineral oil T=20°C;

triethylamine in water T=20°C;

sodium hydride in tetrahydrofuran 24 h; Ambient temperature;