2-甲基-3,4-二氢-2H-1-萘酮合成路线 （共 89 条）
反应条件
1: 80 percent / perchloric acid / CCl4 / 10 h 2: 18 percent / hydrogen / Pd/BaSO4 / toluene / 48 h View Scheme
参考文献
Tishler; Fieser; Wendler
Journal of the American Chemical Society, 1940 , vol. 62, p. 2866,2868
反应条件
toluene-4-sulfonic acid; 3-hydroxy-2,2-dimethylpropanol in toluene
36 h; Reflux;
参考文献
Imai, Masao; Morais, Goreti Ribeiro; Al-Hindawi, Bassam; Al-Sulaibi, Mazen A.M.; Meetani, Mohammad; Thiemann, Thies
Journal of Chemical Research, 2010 , # 6 p. 325 - 329
反应条件
1: KOtBu / benzene
2: (i) LiAlH4, (ii) KHSO4
3: SeO2
View Scheme
参考文献
Christol,H. et al.
Bulletin de la Societe Chimique de France, 1960 , p. 1696 - 1699
反应条件
1: 92.2 percent / NaH / various solvent(s) / 0.5 h / Heating
2: 62.8 percent / H2
View Scheme
参考文献
Morin,F.G.; Horton,W.J.; Grant,D.M.
Journal of the American Chemical Society, 1983 , vol. 105, p. 3992
反应条件
sodium hydride in various solvent(s)
0.5 h; Heating;
参考文献
Morin,F.G.; Horton,W.J.; Grant,D.M.
Journal of the American Chemical Society, 1983 , vol. 105, p. 3992
反应条件
1.1: NaH / tetrahydrofuran; hexamethylphosphoric acid triamide
1.2: tetrahydrofuran; hexamethylphosphoric acid triamide
2.1: SmI2 / tetrahydrofuran
3.1: Et3N / CH2Cl2
4.1: 26 percent / 9,10-dicyanoanthracene; biphenyl; Cu(OAc)2 / acetonitrile / Irradiation
View Scheme
参考文献
Hasegawa, Eietsu; Yamaguchi, Naoto; Muraoka, Hiroyasu; Tsuchida, Hiroyuki
Organic Letters, 2007 , vol. 9, # 15 p. 2811 - 2814
反应条件
2: aq. H2SO4
View Scheme
参考文献
Christol,H. et al.
Bulletin de la Societe Chimique de France, 1960 , p. 1696 - 1699
反应条件
18-crown-6 ether; superoxyde de potassium in tetrahydrofuran
5 h; Ambient temperature; Mechanism;
参考文献
Hocquaux, Michel; Jacquet, Bernard; Vidril-Robert, Daniele; Maurette, Marie-Therese; Oliveros, Esther
Tetrahedron Letters, 1984 , vol. 25, # 5 p. 533 - 536
反应条件
lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
参考文献
Cheon, Cheol Hong; Kanno, Osamu; Toste, F. Dean
Journal of the American Chemical Society, 2011 , vol. 133, # 34 p. 13248 - 13251
反应条件
triethylamine in anhydrous dichloroethane
12 h; CoolingReflux;
参考文献
Buttke, Klaus; Niclas, Hans-Joachim
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1998 , vol. 340, # 7 p. 669 - 675
