2-苄氧基羰基氨基-3-叔丁氧基羰基氨基-丙酸合成路线 （共 5 条）
反应条件
potassium carbonate in 1,4-dioxane Acylation;
参考文献
Ho, Jonathan Z.; Levy, Odile E.; Gibson, Tony S.; Nguyen, Khanh; Semple, J. Edward
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 24 p. 3459 - 3464
反应条件
1: [bis(trifluoroacetoxy)iodo]-benzene; pyridine / dimethylformamide; H2O / 4.5 h / 20 °C 2: Na2CO3 / H2O; dioxane / 20 °C View Scheme
参考文献
Zhang, Zhenyu; Aerschot, Arthur Van; Hendrix, Chris; Busson, Roger; David, Frank; Sandra, Pat; Herdewijn, Piet
Tetrahedron, 2000 , vol. 56, # 16 p. 2513 - 2522
反应条件
1: Na2CO3 / H2O; dioxane / 20 °C 2: [bis(trifluoroacetoxy)iodo]-benzene; pyridine / dimethylformamide; H2O / 4.5 h / 20 °C 3: Na2CO3 / H2O; dioxane / 20 °C View Scheme
参考文献
Zhang, Zhenyu; Aerschot, Arthur Van; Hendrix, Chris; Busson, Roger; David, Frank; Sandra, Pat; Herdewijn, Piet
Tetrahedron, 2000 , vol. 56, # 16 p. 2513 - 2522
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US6384080 B1, 2002 ;
反应条件
trifluoroacetic acid
参考文献
Brtnik,F.; Zaoral,M.
Collection of Czechoslovak Chemical Communications, 1976 , vol. 41, p. 2969 - 2977
