5-氰基-2-甲基-6-(甲基硫代)嘧啶-4(3H)-酮合成路线 (共 8 条)
反应条件
hydrogenchloride; triethylamine in ethanol Heating;
参考文献
Kohra, Shinya; Tominaga, Yoshinori; Hosomi, Akira
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 959 - 968
反应条件
sodium hydride in N,N-dimethyl-formamide 96 h; Ambient temperature;
参考文献
Lorente, Antonio; Garcia, M. Luisa; Fernandez, Misericordia; Soto, Jose L.
Heterocycles, 1992 , vol. 34, # 8 p. 1573 - 1582
反应条件
1: ethanimidamide With sodium hydride in N,N-dimethyl-formamide 0.5 h; 2: ethyl 2-cyano-3,3-bis(methylthio)-2-propenoate in N,N-dimethyl-formamide T=10°C; 4 h; Cooling;
参考文献
Shanmugasundaram; Harikrishnan; Vijey Aanandini; Sathish, Kumar M.; Sateesh
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 3 p. 284 - 289
反应条件
triethylamine in ethanol 5 h; Heating;
参考文献
Ram, Vishnu J; Haque, Navedul; Nath, Mahendra
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 7 p. 754 - 759
参考文献
Ram, Vishnu J; Haque, Navedul; Nath, Mahendra
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 7 p. 754 - 759
反应条件
sodium hydride 1.) benzene, N,N-dimethylacetamide, room temperature; 2.) methanol, reflux; Yield given. Multistep reaction;
参考文献
Kohra, Shinya; Tominaga, Yoshinori; Hosomi, Akira
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 959 - 968
反应条件
N,N-diethylaniline; trichlorophosphate 3 h; Heating;
参考文献
Ram, Vishnu J; Haque, Navedul; Nath, Mahendra
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 7 p. 754 - 759
反应条件
in ethylene glycol dimethyl ether
Heating;
参考文献
Bagli, Jehan; Bogri, T.; Palameta, B.; Rakhit, S.; Peseckis, S.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 4 p. 814 - 823