2-苯基-1-乙炔硼酸频那醇酯合成路线 （共 36 条）
反应条件
1: phenylacetylene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran; hexane T=-78°C; 2 h; Further stages.;
参考文献
Nishihara, Yasushi; Miyasaka, Mitsuru; Okamoto, Masanori; Takahashi, Hideki; Inoue, Eiji; Tanemura, Kenki; Takagi, Kentaro
Journal of the American Chemical Society, 2007 , vol. 129, # 42 p. 12634 - 12635
反应条件
C31H43IrN2Si in toluene T=20°C; 0.216667 h; GloveboxInert atmosphere; Reagent/catalystSolventConcentrationTime; chemoselective reaction;
参考文献
Lee, Chun-I; Zhou, Jia; Ozerov, Oleg V.
Journal of the American Chemical Society, 2013 , vol. 135, # 9 p. 3560 - 3566
反应条件
1,3-dimethyl-imidazolidin-2-one; potassium carbonate; triphenylphosphine; copper(l) chloride T=120°C; 12 h;
参考文献
Ogawa, Daisuke; Li, Jing; Suetsugu, Masato; Jiao, Jiao; Iwasaki, Masayuki; Nishihara, Yasushi
Tetrahedron Letters, 2013 , vol. 54, # 6 p. 518 - 521
反应条件
copper(l) chloride in DMI T=120°C; 0.5 h; Inert atmosphere;
参考文献
Nishihara, Yasushi; Saito, Daisuke; Inoue, Eiji; Okada, Yoshiaki; Miyazaki, Mikihiro; Inoue, Yoshiaki; Takagi, Kentaro
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 306 - 308
反应条件
copper(l) chloride in DMI T=120°C; 0.5 h; Inert atmosphere;
参考文献
Nishihara, Yasushi; Saito, Daisuke; Inoue, Eiji; Okada, Yoshiaki; Miyazaki, Mikihiro; Inoue, Yoshiaki; Takagi, Kentaro
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 306 - 308
反应条件
1.1: zirconocene dichloride; n-butyllithium; tributylphosphine / tetrahydrofuran; hexane / 1 h / 50 °C / |Schlenk technique; |Inert atmosphere 1.2: 1 h / 50 °C / |Schlenk technique; |Inert atmosphere 2.1: RuCl2(tricyclohexylphosphine)2(benzylidene) / dichloromethane / 1 h / 20 °C / |Schlenk technique; |Inert atmosphere 3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydroxide / tetrahydrofuran; water / 24 h / 20 °C / |Schlenk technique; |Inert atmosphere 4.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.5 h / 20 °C / |Schlenk technique; |Inert atmosphere 5.1: molybdenum pentachloride / dichloromethane / 12 h / 20 °C / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Nishihara, Yasushi; Suetsugu, Masato; Saito, Daisuke; Kinoshita, Megumi; Iwasaki, Masayuki
Organic Letters, 2013 , vol. 15, # 10 p. 2418 - 2421
反应条件
1,3-dimethyl-imidazolidin-2-one; potassium carbonate; triphenylphosphine; copper(l) chloride T=120°C; 12 h;
参考文献
Tetrahedron Letters, , vol. 54, # 6 p. 518 - 521
反应条件
1,3-dimethyl-imidazolidin-2-one; potassium carbonate; triphenylphosphine; copper(l) chloride T=120°C; 12 h;
参考文献
Ogawa, Daisuke; Li, Jing; Suetsugu, Masato; Jiao, Jiao; Iwasaki, Masayuki; Nishihara, Yasushi
Tetrahedron Letters, 2013 , vol. 54, # 6 p. 518 - 521
反应条件
1: benzyl azide; 4,4,5,5-tetramethyl-2-(2-phenylethynyl)-[1,3,2]-dioxaborolane in 1,2-dichloro-benzene T=150°C; 24 h; Inert atmosphere; 2: iodobenzene With potassium phosphate; Pd2(dba)3; [(t-Bu)3PH]BF4 in 1,2-dichloro-benzene; acetonitrile T=50°C; 16 h; Inert atmosphere;
参考文献
Huang, Jianhui; Macdonald, Simon J.F.; Cooper, Anthony W.J.; Fisher, Gail; Harrity, Joseph P.A.
Tetrahedron Letters, 2009 , vol. 50, # 39 p. 5539 - 5541
反应条件
1.1: Schwartz's reagent / tetrahydrofuran / 1 h / 20 °C / |Inert atmosphere 1.2: 1 h / 20 °C / |Inert atmosphere 2.1: hydrogen; C30H40IrNO2P(1+)*C32H12BF24(1-) / dichloromethane / 18 h / 50 °C / 22502.3 Torr View Scheme
参考文献
Roseblade, Stephen J.; Smilovic, Ivana Gazic; Casar, Zdenko
Tetrahedron, 2014 , vol. 70, # 16 p. 2654 - 2660
