4-乙酰基-5-甲基异恶唑-3-甲酸乙酯合成路线 （共 11 条）
反应条件
sodium ethanolate in ethanol
参考文献
Burkhart, David J.; Zhou, Peiwen; Blumenfeld, Alex; Twamley, Brendan; Natale, Nicholas R.
Tetrahedron, 2001 , vol. 57, # 38 p. 8039 - 8046
反应条件
ethanol; sodium T=20°C; 96 h; Inert atmosphere;
参考文献
Matti, Afnan A.; Mirzaei, Joseph; Rudolph, John; Smith, Stephen A.; Newell, Jayme L.; Patel, Sarjubhai A.; Braden, Michael R.; Bridges, Richard J.; Natale, Nicholas R.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 21 p. 5931 - 5935
反应条件
toluene-4-sulfonic acid in acetone
参考文献
Zhou, Peiwen; Natale
Tetrahedron Letters, 1998 , vol. 39, # 45 p. 8249 - 8252
反应条件
1-methyl-piperidine; copper diacetate in chloroform T=60°C; 72 h;
参考文献
Trogu, Elena; Cecchi, Luca; De Sarlo, Francesco; Guideri, Luca; Ponticelli, Fabio; Machetti, Fabrizio
European Journal of Organic Chemistry, 2009 , # 34 p. 5971 - 5978
反应条件
sodium ethanolate in ethanol
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 6 p. 1055 - 1059
反应条件
in ethanol T=5 - 10°C;
参考文献
Gazzetta Chimica Italiana, , vol. 95, p. 1478 - 1491
反应条件
in ethanol 0.0833333 h; Heating;
参考文献
Renzi,G.; Pinzanti,S.
Farmaco, Edizione Scientifica, 1969 , vol. 24, p. 885 - 892
反应条件
hydrazine hydrate in ethanol 0.0333333 h; Heating;
参考文献
Feixas, Joan; Giovannoni, Maria Paola; Vergelli, Claudia; Gavalda, Amadeu; Cesari, Nicoletta; Graziano, Alessia; Dal Piaz, Vittorio
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 9 p. 2381 - 2384
参考文献
Patel, Sarjubhai A.; Rajale, Trideep; O'Brien, Erin; Burkhart, David J.; Nelson, Jared K.; Twamley, Brendan; Blumenfeld, Alex; Szabon-Watola, Monika I.; Gerdes, John M.; Bridges, Richard J.; Natale, Nicholas R.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 1 p. 202 - 213
反应条件
potassium acetate in ethanol 2 h; Heating;
参考文献
Renzi,G.; Dal Piaz,V.
Gazzetta Chimica Italiana, 1965 , vol. 95, p. 1478 - 1491
