(S)-(-)-1-萘基-1-乙醇合成路线 （共 81 条）
反应条件
Y(salen)(N(SiMe2H)2)(THF) in toluene T=-3°C; 17 h; Product distribution; Further Variations:CatalystsReaction partnersSolventsReagentstimes;
参考文献
Organic Letters, , vol. 4, # 9 p. 1607 - 1610
反应条件
endo-8,8-dimethyl-2-phenylphosphabicyclo[3.3.0]-octane in toluene T=-25°C; Activation energyProduct distribution; Further Variations:ReagentsTemperaturesSolvents;
参考文献
Journal of Organic Chemistry, , vol. 68, # 13 p. 5020 - 5027
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C / |Inert atmosphere 2: lipase from candida antartica / aq. phosphate buffer / 48 h / 30 °C View Scheme
参考文献
Letters in Organic Chemistry, , vol. 9, # 9 p. 615 - 621
参考文献
Helvetica Chimica Acta, , vol. 64, # 7 p. 2485 - 2488
反应条件
(1R,2R)-α,α,α',α'-tetraphenyl-1,2-cyclohexanedimethanol; TiF4 in CH3CN 1) THF, hexane, 0 deg C to RT, 20 min, 2) THF, hexane, 20 min, 3) THF, hexane, -10 deg C, 12 h then warm to RT; Yield givenMultistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 39, # 52 p. 9593 - 9596
反应条件
{3-[2-(3,5-dimethylphenyl)naphthalen-1-yl]pyridin-4-yl}diethylamine; triethylamine in toluene T=-78°C; 8 h; optical yield given as percent ee;
参考文献
Journal of the American Chemical Society, , vol. 134, # 22 p. 9390 - 9399
反应条件
Candida antarctica lipase B in n-heptane T=60°C; 3 h; Microwave irradiationResolution of racemateEnzymatic reaction; Kinetics; Reagent/catalystTemperatureSolvent; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 81, p. 58 - 65
反应条件
sodium tetrahydroborate in solid 120 h; Ambient temperatureother variant: ultrasonic irradiation, 2 d; Product distribution;
参考文献
Carbohydrate Research, , vol. 192, p. 363 - 365
反应条件
isopropyl alcohol; trans-1-Hydroxy-1-phenyl-2-tosylaminopropan 1.) ether, 30 min, -30 to -10 grad C, 2.) from -78 grad C to room temp., overnight; Further sulphonamide derivatives of norephedrine were investigated.; Product distribution;
参考文献
Tetrahedron Letters, , vol. 27, # 47 p. 5711 - 5714
反应条件
AZADO; oxygen in aq. acetate buffer T=20°C; pH=4.5; 8 h; Green chemistryEnzymatic reaction; Reagent/catalyst; chemoselective reaction;
参考文献
Zhu, Chenjie; Zhang, Zhi; Ding, Weiwei; Xie, Jingjing; Chen, Yong; Wu, Jinglan; Chen, Xiaochun; Ying, Hanjie
Green Chemistry, 2014 , vol. 16, # 3 p. 1131 - 1138
