1,4-二氧杂螺[4.4]壬烷-7-甲腈合成路线 (共 3 条)
反应条件
toluene-4-sulfonic acid in benzene 48 h; Heating;
参考文献
Zimmerman, Howard E.; Zhu, Zhaoning
Journal of the American Chemical Society, 1995 , vol. 117, # 19 p. 5245 - 5262
反应条件
1: 68 percent / Na2CO3 / methanol / 0 °C 2: 90 percent / H+ View Scheme
参考文献
Della; Knill
Australian Journal of Chemistry, 1994 , vol. 47, # 10 p. 1833 - 1841
反应条件
1: 98 percent / 10percent NaOH / 3 h / Heating
2: 1.) 25percent aq. NaOH / 1.) HMPA, 2.) HMPA, 1 h
View Scheme
参考文献
Della; Knill
Australian Journal of Chemistry, 1994 , vol. 47, # 10 p. 1833 - 1841