N-(3-甲基-2-丁烯基)邻苯二甲酰亚胺合成路线 （共 14 条）
反应条件
in N,N-dimethyl-formamide T=120 - 160°C; 19 h;
参考文献
Coxon, Geoffrey D.; Furman, Brian L.; Harvey, Alan L.; McTavish, John; Mooney, Mark H.; Arastoo, Mahmoud; Kennedy, Alan R.; Tettey, Justice M.; Waigh, Roger D.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 11 p. 3457 - 3463
反应条件
in N,N-dimethyl-formamide 12 h; Reflux;
参考文献
SANOFI; EL-AHMAD, Youssef; FILOCHE-ROMME, Bruno; LETALLEC, Jean-Philippe; MARCINIAK, Gilbert; RONAN, Baptiste; VIVET, Bertrand
Patent: WO2013/190510 A2, 2013 ;
Location in patent: Page/Page column 122-123 ;
反应条件
potassium fluoride on basic alumina in 2-methyl tetrahydrofuran T=90°C; 4 h; Inert atmosphere; chemoselective reaction;
参考文献
Pace, Vittorio; Hoyos, Pilar; Fernandez, Maria; Sinisterra, Jose V.; Alcantara, Andres R.
Green Chemistry, 2010 , vol. 12, # 8 p. 1380 - 1382
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; 1,3-bis-(diphenylphosphino)propane; sodium carbonate in toluene T=120°C; 10 h; Inert atmosphere; regioselective reaction;
参考文献
Banerjee, Debasis; Junge, Kathrin; Beller, Matthias
Angewandte Chemie - International Edition, 2014 , vol. 53, # 6 p. 1630 - 1635
Angew. Chem., 2014 , vol. 126, # 6 p. 1656 - 1661,6
反应条件
1: 77.5 percent / PBr3 / diethyl ether / 1.) 0 deg C, 0.5 h, 2.) 25 deg C, 3.) reflux, 1 h 2: dimethylformamide / 1.) stirring overnight, 2.) 60 deg C, 1 h View Scheme
参考文献
Stille, J. K.; Becker Y.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2139 - 2145
反应条件
1: HBr, AcOH 2: dimethylformamide View Scheme
参考文献
Kennewell, Peter D.; Matharu, Saroop S.; Taylor, John B.; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2542 - 2548
参考文献
Goemoery; Jezo
Chemicke Zvesti, 1953 , vol. 7, p. 41
Chem.Abstr., 1955 , p. 6185
反应条件
xylene T=169°C; zuletzt auf 218grad;
参考文献
Spaeth; Spitzy
Chemische Berichte, 1925 , vol. 58, p. 2275
反应条件
in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
Liu, Na; Wang, Hao-Yuan; Zhang, Wei; Jia, Zhi-Hong; Guzei, Ilia A.; Xu, Hua-Dong; Tang, Weiping
Chirality, 2013 , vol. 25, # 11 p. 805 - 809
反应条件
1: phosphorus (III)-chloride 2: xylene / 220 °C View Scheme
参考文献
Goemoery; Jezo
Chemicke Zvesti, 1953 , vol. 7, p. 41
Chem.Abstr., 1955 , p. 6185
