4-乙酰氧基-1-羟基-9-氧代-7,10-二[(三乙基硅烷基)氧基]-13-[(三甲基硅烷基)氧基]-5,20-环氧紫杉-11-烯-2-基苯甲酸酯合成路线 (共 3 条)
反应条件
1H-imidazole; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0°C; 0.5 h;
参考文献
Florida State University
Patent: US6727369 B1, 2004 ;
Location in patent: Page column 39 - 40 ;
反应条件
1: in tetrahydrofuran; diethyl ether; cyclohexane T=-45°C; 1 h; 2: With sodium hydrogencarbonate in tetrahydrofuran; diethyl ether; cyclohexane; water
参考文献
Florida State University
Patent: US6727369 B1, 2004 ;
Location in patent: Page column 43 ;
反应条件
1: With sodium bis(2-methoxyethoxy)aluminium dihydride in tetrahydrofuran; toluene T=0°C; 1 h; 2: With sodium hydrogencarbonate in tetrahydrofuran; water; toluene
参考文献
Florida State University
Patent: US6727369 B1, 2004 ;
Location in patent: Page column 40 - 41 ;