1-甲基-4-(1-甲基丙基)苯合成路线 （共 47 条）
反应条件
silica-supported aluminum chloride in dichloromethane T=140°C; Friedel-Crafts Alkylation; 0.0833333 h; Microwave irradiation;
参考文献
Zupp, Laurine R.; Campanella, Veronica L.; Rudzinski, Diandra M.; Beland, Franois; Priefer, Ronny
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5343 - 5346
反应条件
1: sec.-butyllithium With indium(III) chloride in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: carbon monoxide; 1-(iodo)-4-methylbenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane T=66°C; P=760 Torr; 3 h;
参考文献
Lee, Phil Ho; Lee, Sung Wook; Lee, Kooyeon
Organic Letters, 2003 , vol. 5, # 7 p. 1103 - 1106
反应条件
iron (III) acetylacetonate in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=80°C; 2 h;
参考文献
Rao Volla, Chandra M.; Vogel, Pierre
Angewandte Chemie - International Edition, 2008 , vol. 47, # 7 p. 1305 - 1307
反应条件
anhydrous iron chloride; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran T=0°C; 3 h; Inert atmosphere;
参考文献
Czaplik, Waldemar Maximilian; Mayer, Matthias; Von Wangelin, Axel Jacobi
Angewandte Chemie - International Edition, 2009 , vol. 48, # 3 p. 607 - 610
反应条件
hydrogen; (S)-4-tert-butyl-2-(2-(di-o-tolylphosphino)phenyl)-4,5-dihydrooxazole; [Ir(COD)]-tetrakis[3,5-bis(trifluoromethyl)phenyl]borate in dichloromethane T=25°C; P=37503 Torr; 1 h;
参考文献
McIntyre, Steven; Hoermann, Esther; Menges, Frederik; Smidt, Sebastian P.; Pfaltz, Andreas
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 2-3 p. 282 - 288
反应条件
silica-supported aluminum chloride in dichloromethane T=140°C; Friedel-Crafts Alkylation; 0.0833333 h; Microwave irradiation; Overall yield = 92 percent;
参考文献
Zupp, Laurine R.; Campanella, Veronica L.; Rudzinski, Diandra M.; Beland, Franois; Priefer, Ronny
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5343 - 5346
反应条件
AlCl3, aluminium chloride in dichloromethane T=140°C; Friedel-Crafts Alkylation; 0.0833333 h; Microwave irradiation; Overall yield = 39 percent;
参考文献
Zupp, Laurine R.; Campanella, Veronica L.; Rudzinski, Diandra M.; Beland, Franois; Priefer, Ronny
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5343 - 5346
反应条件
1: sec-butyl bromide With C33H49N2O2(1+)*Cl4Fe(1-) in diethyl ether T=0°C; Grignard Reaction; 0.0333333 h; 2: (4-Methylphenyl)-magnesium bromide in diethyl ether T=0 - 30°C; Grignard Reaction;
参考文献
Deng, Hai-Ning; Xing, Ya-Lin; Xia, Cong-Liang; Sun, Hong-Mei; Shen, Qi; Zhang, Yong
Dalton Transactions, 2012 , vol. 41, # 38 p. 11597 - 11607
反应条件
boron trifluoride T=75°C;
参考文献
Meyer,H.; Bernhauer
Monatshefte fuer Chemie, 1929 , vol. 53/54, p. 728
反应条件
Me4-DACH; magnesium; cobalt(II) chloride in tetrahydrofuran T=0°C; Inert atmosphere;
参考文献
Czaplik, Waldemar Maximilian; Mayer, Matthias; Jacobi Von Wangelin, Axel
Synlett, 2009 , # 18 p. 2931 - 2934
