二氯双(三甲基硅基)甲烷合成路线 （共 34 条）
反应条件
LiDBB 1.) THF, -90 deg C; 2.) THF, -80 deg C; other electrophiles and temperature; Product distribution;
参考文献
Tetrahedron Letters, , vol. 29, # 41 p. 5237 - 5240
反应条件
chloro-trimethyl-silane; LiDBB 1.) THF, -90 deg C; 2.) THF, -80 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Eikema Hommes, N. J. R. van; Bickelhaupt, F.; Klumpp, G. W.
Tetrahedron Letters, 1988 , vol. 29, # 41 p. 5237 - 5240
反应条件
LiDBB 1.) THF, -90 deg C; 2.) THF, -80 deg C; other electrophiles and temperature; Product distribution;
参考文献
Eikema Hommes, N. J. R. van; Bickelhaupt, F.; Klumpp, G. W.
Tetrahedron Letters, 1988 , vol. 29, # 41 p. 5237 - 5240
反应条件
n-butyllithium 1.) hexane, THF, Et2O, n-pentane, -110 deg C, 2 h, 2.) hexane, THF, Et2O, n-pentane, a) -110 deg C, 30 min, b) -110 deg C - RT, overnight; Multistep reaction. Title compound not separated from byproducts;
参考文献
Eaborn, Colin; Jones, Karen L.; Lickiss, Paul D.
Journal of Organometallic Chemistry, 1994 , vol. 466, # 1-2 p. 35 - 42
反应条件
1.) hexane, THF, Et2O, n-pentane, -110 deg C, 2 h, 2.) hexane, THF, Et2O, n-pentane, a) -110 deg C, 30 min, b) -110 deg C - RT, overnight; Multistep reaction. Title compound not separated from byproducts;
参考文献
Eaborn, Colin; Jones, Karen L.; Lickiss, Paul D.
Journal of Organometallic Chemistry, 1994 , vol. 466, # 1-2 p. 35 - 42
反应条件
LiDBB
1.) THF, -90 deg C; 2.) THF, -80 deg C; Yield given. Multistep reaction;
参考文献
Eikema Hommes, N. J. R. van; Bickelhaupt, F.; Klumpp, G. W.
Tetrahedron Letters, 1988 , vol. 29, # 41 p. 5237 - 5240
反应条件
1: 36 percent / 1M nBuLi / hexane; tetrahydrofuran; diethyl ether; pentane / 2 h / -110 - -80 °C
2: 97 percent / Br2 / CCl4; CH2Cl2 / 0.25 h
3: 84 percent / CH2Cl2 / 24 h
4: 41 percent / 1.6M nBuLi / hexane; tetrahydrofuran; diethyl ether; pentane / 1.) -100 deg C, 1 h, 2.) RT
5: 1 h
View Scheme
参考文献
Eaborn, Colin; Reed, David E.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1985 , p. 1687 - 1694
反应条件
in diethyl ether
Heating;
参考文献
Al-Hashimi,S.; Smith,J.D.
Journal of Organometallic Chemistry, 1978 , vol. 153, p. 253 - 263
反应条件
n-butyllithium in tetrahydrofuran; diethyl ether; hexane
T=-110°C; 2 h;
参考文献
Appel, Rolf; Gaitzsch, Thomas; Knoch, Frank; Lenz, Gerhard
Chemische Berichte, 1986 , vol. 119, # 6 p. 1977 - 1985
反应条件
lithium in tetrahydrofuran
T=-80°C;
参考文献
Eikema Hommes, N. J. R. van; Bickelhaupt, F.; Klumpp, G. W.
Tetrahedron Letters, 1988 , vol. 29, # 41 p. 5237 - 5240
