2,3-二氢-3-氧代螺[1H-茚-1,4’-哌啶]-1’-甲酸叔丁酯合成路线 （共 2 条）
反应条件
1: With tetrabutylammomium bromide; water; trifluoroacetic acid in dichloromethane T=20°C; 4 h; 2: With water in diethyl ether; dichloromethane 3: With potassium hydroxide in water
参考文献
VERTEX PHARMACEUTICALS, INCORPORATED
Patent: WO2006/23852 A2, 2006 ;
Location in patent: Page/Page column 84; 85 ;
WO 2006/023852 A2
反应条件
hydrogenchloride; methanol
参考文献
VERTEX PHARMACEUTICALS, INCORPORATED
Patent: WO2006/23852 A2, 2006 ;
Location in patent: Page/Page column 105; 106 ;
WO 2006/023852 A2
