3,4-二甲氧基苯乙酸甲酯合成路线 （共 36 条）
反应条件
in methanol T=65°C; 4 h; Yield given. Yields of byproduct given;
参考文献
Helvetica Chimica Acta, , vol. 81, # 2 p. 251 - 267
反应条件
1: aq.-ethanolic KOH-solution 2: hydrogen chloride View Scheme
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 271, p. 431,435
反应条件
sodium hydroxide; dihydrogen peroxide Erwaermen des Reaktionsprodukts mit Methanol unter Zusatz von Schwefelsaeure;
参考文献
Org. Synth. Coll. Vol., , vol. II, p. 333,334
反应条件
1: 6.9 percent / PPA / 0.25 h / Heating 2: 10percent aq. NaOH / 4 h / Heating View Scheme
参考文献
Nizamuddin, S.; Ghosal, M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 5 p. 431 - 432
反应条件
1: (i) LiAlH4, Et2O, (ii) aq. H2SO4 2: SOCl2, PhNMe2 / CHCl3 View Scheme
参考文献
Campaigne,E.; Heaton,B.G.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2372 - 2378
反应条件
1: (i) LiAlH4, Et2O, (ii) aq. H2SO4 2: SOCl2, PhNMe2 / CHCl3 3: NaI / ethanol 4: H2O; ethanol 5: aq. KOH / methanol View Scheme
参考文献
Sargent,L.J.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1754 - 1758
反应条件
1: With sodium carbonate in tetrahydrofuran T=80°C; 10 h; 2: With hydrogenchloride; water
参考文献
Yang, Jian; Yang, Jing Xiang; Zhang, Fang; Chen, Gang; Pan, Wei; Yu, Rui; Wu, Shuwen; Tien, Po
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 12 p. 2680 - 2684
反应条件
sodium tetrahydroborate; calcium chloride in ethanol T=0 - 20°C; 16 h;
参考文献
Kapadia, Nirav; Harding, Wayne
Tetrahedron, 2013 , vol. 69, # 42 p. 8914 - 8920
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 431,435
反应条件
hydrazine hydrate T=110 - 120°C;
参考文献
Prata, Jose V.; Clemente, Dina-Telma S.; Prabhakar, Sundaresan; Lobo, Ana M.; Mourato, Isabel; Branco, Paula S.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 4 p. 513 - 528
