1-(2,3-二氨基苯基)乙酮合成路线 （共 7 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol 2 h;
参考文献
MERCK SERONO S.A.; THUNUGUNTLA, Siva Sanjeeva Rao; SUBRAMANYA, Hosahalli; KUNNAM, Satish Reddy; SANIVARU VIJAY, Sekhar Reddy; BINGI, Chakrapani; KUSANUR, Raviraj; SCHWARZ, Matthias; ARLT, Michael
Patent: WO2010/115736 A2, 2010 ;
Location in patent: Page/Page column 121-122 ;
WO 2010/115736 A2
反应条件
palladium 10 on activated carbon; hydrogen in methanol 2 h; Inert atmosphere;
参考文献
Wang, Jingjing; Chen, Weiqiang; Zuo, Sujing; Liu, Lu; Zhang, Xinrui; Wang, Jianhui
Angewandte Chemie - International Edition, 2012 , vol. 51, # 49 p. 12334 - 12338
Angew. Chem., 2012 , vol. 124, # 49 p. 12500 - 12504,5
反应条件
1: aqueous hydrochloric acid 2: iron; aqueous acetic acid View Scheme
参考文献
Wang, Jingjing; Chen, Weiqiang; Zuo, Sujing; Liu, Lu; Zhang, Xinrui; Wang, Jianhui
Angewandte Chemie - International Edition, 2012 , vol. 51, # 49 p. 12334 - 12338
Angew. Chem., 2012 , vol. 124, # 49 p. 12500 - 12504,5
反应条件
1: nitric acid / 0.25 h / 0 °C / |Inert atmosphere 2: hydrogenchloride / ethanol; water / 1 h / |Reflux; |Inert atmosphere 3: palladium 10 on activated carbon; hydrogen / methanol / 2 h / |Inert atmosphere View Scheme
参考文献
Wang, Jingjing; Chen, Weiqiang; Zuo, Sujing; Liu, Lu; Zhang, Xinrui; Wang, Jianhui
Angewandte Chemie - International Edition, 2012 , vol. 51, # 49 p. 12334 - 12338
Angew. Chem., 2012 , vol. 124, # 49 p. 12500 - 12504,5
反应条件
1: triethylamine / dichloromethane / 2 h / 20 °C / |Inert atmosphere 2: nitric acid / 0.25 h / 0 °C / |Inert atmosphere 3: hydrogenchloride / ethanol; water / 1 h / |Reflux; |Inert atmosphere 4: palladium 10 on activated carbon; hydrogen / methanol / 2 h / |Inert atmosphere View Scheme
参考文献
Wang, Jingjing; Chen, Weiqiang; Zuo, Sujing; Liu, Lu; Zhang, Xinrui; Wang, Jianhui
Angewandte Chemie - International Edition, 2012 , vol. 51, # 49 p. 12334 - 12338
Angew. Chem., 2012 , vol. 124, # 49 p. 12500 - 12504,5
反应条件
1: aq.-ethanolic hydrochloric acid 2: iron; aqueous acetic acid View Scheme
参考文献
Simpson
Journal of the Chemical Society, 1947 , p. 237
反应条件
1: sulfuric acid; nitric acid 2: aq.-ethanolic hydrochloric acid 3: iron; aqueous acetic acid View Scheme
参考文献
Simpson
Journal of the Chemical Society, 1947 , p. 237
