4-氯-7-氟-6-甲氧基喹唑啉合成路线 （共 7 条）
参考文献
ZENECA LIMITED
Patent: EP635498 A1, 1995 ;
EP 0635498 A1
反应条件
1: 89 percent / hydrogen / Pd/C / ethanol / 6 h / 20 °C 2: 68 percent / acetic acid / 135 °C 3: 95 percent / SOCl2 / 16 h / Heating View Scheme
参考文献
Harris, Craig S.; Kettle, Jason G.; Williams, Emma J.
Tetrahedron Letters, 2005 , vol. 46, # 43 p. 7381 - 7384
反应条件
1: 95 percent / H2SO4 / 16 h / Heating 2: 62 percent / HNO3; H2SO4 / 0.5 h / 0 - 10 °C 3: 89 percent / hydrogen / Pd/C / ethanol / 6 h / 20 °C 4: 68 percent / acetic acid / 135 °C 5: 95 percent / SOCl2 / 16 h / Heating View Scheme
参考文献
Harris, Craig S.; Kettle, Jason G.; Williams, Emma J.
Tetrahedron Letters, 2005 , vol. 46, # 43 p. 7381 - 7384
反应条件
1: 62 percent / HNO3; H2SO4 / 0.5 h / 0 - 10 °C 2: 89 percent / hydrogen / Pd/C / ethanol / 6 h / 20 °C 3: 68 percent / acetic acid / 135 °C 4: 95 percent / SOCl2 / 16 h / Heating View Scheme
参考文献
Harris, Craig S.; Kettle, Jason G.; Williams, Emma J.
Tetrahedron Letters, 2005 , vol. 46, # 43 p. 7381 - 7384
参考文献
Zeneca Limited
Patent: US5580870 A1, 1996 ;
US 5580870 A
参考文献
ZENECA LIMITED
Patent: EP635498 A1, 1995 ;
EP 0635498 A1
参考文献
ZENECA LIMITED
Patent: EP635498 A1, 1995 ;
EP 0635498 A1
