3-(4-氟苯甲酰基)苯甲酸合成路线 （共 3 条）
反应条件
1: With sodium hydroxide in tetrahydrofuran T=20°C; 16 h; 2: With hydrogenchloride in water
参考文献
PROSIDION LIMITED; BLOXHAM, Jason; BRADLEY, Stuart Edward; SAMBROOK-SMITH, Colin Peter; SMYTH, Donald; KEILY, John; DAWSON, Graham John; RASAMISON, Chrystelle Marie; BELL, James Charles
Patent: WO2011/117254 A1, 2011 ;
Location in patent: Page/Page column 45 ;
WO 2011/117254 A1
反应条件
1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C 2: triethylamine / dichloromethane / 2 h 3: tetrahydrofuran / 1 h / -78 - 20 °C 4: sodium hydroxide / tetrahydrofuran / 16 h / 20 °C View Scheme
参考文献
PROSIDION LIMITED; BLOXHAM, Jason; BRADLEY, Stuart Edward; SAMBROOK-SMITH, Colin Peter; SMYTH, Donald; KEILY, John; DAWSON, Graham John; RASAMISON, Chrystelle Marie; BELL, James Charles
Patent: WO2011/117254 A1, 2011 ;
WO 2011/117254 A1
反应条件
1: triethylamine / dichloromethane / 2 h 2: tetrahydrofuran / 1 h / -78 - 20 °C 3: sodium hydroxide / tetrahydrofuran / 16 h / 20 °C View Scheme
参考文献
PROSIDION LIMITED; BLOXHAM, Jason; BRADLEY, Stuart Edward; SAMBROOK-SMITH, Colin Peter; SMYTH, Donald; KEILY, John; DAWSON, Graham John; RASAMISON, Chrystelle Marie; BELL, James Charles
Patent: WO2011/117254 A1, 2011 ;
WO 2011/117254 A1
