(S)-2-((((9h-芴-9-基)甲氧基)羰基)氨基)-6-(((4-甲氧基苯基)二苯基甲基)氨基)己酸合成路线 (共 1 条)
反应条件
1: N-(9-fluorenylmethoxycarbonyl)-L-lysine With chloro-trimethyl-silane in dichloromethane T=20 - 50°C; 1 h; Heating / reflux; 2: diphenyl-(4-methoxyphenyl)-methyl chloride With N-ethyl-N,N-diisopropylamine in dichloromethane T=0 - 20°C;
参考文献
Weinshenker, Ned M.; West, Frederick G.; Araneo, Barbara A.; Li, Weiping
Patent: US2005/54607 A1, 2005 ;
Location in patent: Page/Page column 17 ;