4-乙酰氧基-2H,3h-吡喃-2,6-二酮合成路线 （共 2 条）
反应条件
T=40°C; Inert atmosphere;
参考文献
GILEAD SCIENCES, INC.; LI, Wenjie; DE CROOS, Philomen; FANDRICK, Keith, R.; GAO, Joe, Ju; HADDAD, Nizar; LU, Zhi-Hui; QU, Bo; RODRIGUEZ, Sonia; SENANAYAKE, Chris, H.; ZHANG, Yongda; TANG, Wenjun
Patent: WO2012/138670 A1, 2012 ;
Location in patent: Page/Page column 58 ;
WO 2012/138670 A1
反应条件
1: acetic acid / 2 h / 35 °C 2: conc. H2SO4 / 1.5 h / 90 °C View Scheme
参考文献
McCort, Gary; Hoornaert, Christian; Aletru, Michel; Denys, Colombe; Duclos, Olivier; Cadilhac, Caroline; Guilpain, Eric; Dellac, Genevieve; Janiak, Philip; Galzin, Anne-Marie; Delahaye, Monique; Guilbert, Frederique; O'Connor, Stephen
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 8 p. 2129 - 2137
